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IL1RN 蛋白

(Interleukin 1 Receptor Antagonist (IL1RN))
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

48 results

IL1RN 宿主: Pig 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, Imm, PC
产品编号 ABIN7389488
 
IL1RN 宿主: 犬 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, Imm, PC
产品编号 ABIN7389476
 
IL1RN 宿主: Cow 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, Imm, PC
产品编号 ABIN7389473
 
IL1RN 宿主: 马 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, Imm, PC
产品编号 ABIN7389479
 
IL1RN 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95% by SDS-PAGE SDS, AcA Active
产品编号 ABIN7596124
 
Animal-Free IL1RN 宿主: 人, 小鼠 宿主: HEK-293 Cells Recombinant >95 % (SDS-PAGE)
产品编号 ABIN7566395
 
IL1RN 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95% by SDS - PAGE SDS, AcA Active
产品编号 ABIN7596305
 
IL1RN 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining Func, STD, AbP, PI Active
产品编号 ABIN2723404
 
IL1RN 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining STD, AbP
产品编号 ABIN2723403
 
IL1RN 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining STD, AbP
产品编号 ABIN2723402
 
IL1RN 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining STD, AbP
产品编号 ABIN2723401
 
IL1RN 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining STD, AbP
产品编号 ABIN2723400
 
IL1RN 宿主: 犬 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, ELISA, IP
产品编号 ABIN3010127
 
IL1RN 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant >97 % as determined by SDS-PAGE and HPLC. Func Active
产品编号 ABIN2830838
 
IL1RN 宿主: 大鼠 宿主: 大肠杆菌(E. Coli) Recombinant WB, SDS
产品编号 ABIN6123863
 
IL1RN 宿主: 人 宿主: 大肠杆菌(E. Coli) > 95 % AcA, CC Active
产品编号 ABIN6239773
 
IL1RN 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) > 95 % AcA, CC Active
产品编号 ABIN6239774
 
IL1RN 宿主: 马 宿主: 大肠杆菌(E. Coli) Recombinant >95 % as determined by SDS-PAGE and HPLC. Func Active
产品编号 ABIN2830529
 
IL1RN 宿主: 猴 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, ELISA, IP
产品编号 ABIN3010131
 
IL1RN 宿主: Cow 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN7584817
 
  • 类型 Protein
    • Protein
  • 应用范围
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • ELISA
    • Immunogen (Imm)
    • Positive Control (PC)
    • Antibody Production (AbP)
    • Standard (STD)
    • Activity Assay (AcA)
    • Functional Studies (Func)
    • Immunoprecipitation (IP)
    • Cell Culture (CC)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Biochemical Assay (BCA)
    • Protein Interaction (PI)
  • 适用
    • Human
    • Mouse
    • Dog
    • Horse
    • Pig
    • Rat
    • Cow
    • Rabbit
    • Cynomolgus
    • Monkey
    • Rhesus Monkey
    • Tursiops truncatus
  • 论文引用
  • 图像
  • Carrier free only
  • 抗体来源
    • Escherichia coli (E. coli)
    • Yeast
    • HEK-293 Cells
    • HEK-293T Cells
    • Wheat germ
  • 抗原表位
    • AA 26-177
    • AA 27-178
    • Transcript Variant 3
    • AA 18-332
    • AA 24-174
    • AA 26-176
    • AA 1-159
    • AA 25-178
    • Monomer
    • Transcript Variant 1
    • Transcript Variant 4
  • 标记
    • His tag
    • 非结合性
    • Myc-DYKDDDDK Tag
    • Fc Tag
    • GST tag
  • 蛋白类型
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • 生物活性
    • Biologically Active
  • Grade
    • Animal-Free
  • Supplier
    • antibodies-online
    • CUSABIO
    • OriGene
    • Abbexa
    • Cloud-Clone

Latest Publications for our IL1RN 蛋白

Wang, Zhen, Fan, Qin, Han, Zhou, Wang, An: "Axl Deficiency Promotes the Neuroinvasion of Japanese Encephalitis Virus by Enhancing IL-1α Production from Pyroptotic Macrophages." in: Journal of virology, Vol. 94, Issue 17, (2020) (PubMed).

Luo, Huang, He, Liu, Chen, Liu, Mi, Li, Sun, Li, Xiang, Su: "Inflammatory Human Umbilical Cord-Derived Mesenchymal Stem Cells Promote Stem Cell-Like Characteristics of Cancer Cells in an IL-1β-Dependent Manner." in: BioMed research international, Vol. 2018, pp. 7096707, (2018) (PubMed).

Hunt, Xu, Finkelstein, Fan, Carroll, Cheng, Eisenman, Demontis: "The glucose-sensing transcription factor MLX promotes myogenesis via myokine signaling." in: Genes & development, Vol. 29, Issue 23, pp. 2475-89, (2015) (PubMed).

Hedl, Abraham: "Nod2-induced autocrine interleukin-1 alters signaling by ERK and p38 to differentially regulate secretion of inflammatory cytokines." in: Gastroenterology, Vol. 143, Issue 6, pp. 1530-43, (2012) (PubMed).

Hedl, Abraham: "Distinct roles for Nod2 protein and autocrine interleukin-1beta in muramyl dipeptide-induced mitogen-activated protein kinase activation and cytokine secretion in human macrophages." in: The Journal of biological chemistry, Vol. 286, Issue 30, pp. 26440-9, (2011) (PubMed).

OShaughnessy, Choudhary, Harper: "Interleukin-1 alpha blockade prevents hyperkeratosis in an in vitro model of lamellar ichthyosis." in: Human molecular genetics, Vol. 19, Issue 13, pp. 2594-605, (2010) (PubMed).

Eisenberg, Brewer, Verderber, Heimdal, Brandhuber, Thompson: "Interleukin 1 receptor antagonist is a member of the interleukin 1 gene family: evolution of a cytokine control mechanism." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 12, pp. 5232-6, (1991) (PubMed).

Carter, Deibel, Dunn, Tomich, Laborde, Slightom, Berger, Bienkowski, Sun, McEwan: "Purification, cloning, expression and biological characterization of an interleukin-1 receptor antagonist protein." in: Nature, Vol. 344, Issue 6267, pp. 633-8, (1990) (PubMed).

Aliases for IL1RN 蛋白

interleukin 1 receptor antagonist (IL1RN) 蛋白
interleukin 1 receptor antagonist (Il1rn) 蛋白
interleukin 1 receptor antagonist-like (IL1RNL) 蛋白
DIRA 蛋白
F630041P17Rik 蛋白
ICIL-1RA 蛋白
IL-1ra 蛋白
IL-1RA 蛋白
IL-1ra3 蛋白
IL-1RN 蛋白
IL1F3 蛋白
IL1RA 蛋白
IL1RN 蛋白
IRAP 蛋白
IRAP1 蛋白
MVCD4 蛋白
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