IL18BP 抗体
(Interleukin 18 Binding Protein (IL18BP))
The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011].
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Latest Publications for our IL18BP 抗体
: "Role of IL-18 in atopic asthma is determined by balance of IL-18/IL-18BP/IL-18R." in: Journal of cellular and molecular medicine, Vol. 22, Issue 1, pp. 354-373, (2019) (PubMed).: "Altered expression of IL-18 binding protein and IL-18 receptor in basophils and mast cells of asthma patients." in: Scandinavian journal of immunology, Vol. 87, Issue 5, pp. e12658, (2018) (PubMed).
: "Blockade of P2X4 Receptors Inhibits Neuropathic Pain-Related Behavior by Preventing MMP-9 Activation and, Consequently, Pronociceptive Interleukin Release in a Rat Model." in: Frontiers in pharmacology, Vol. 8, pp. 48, (2017) (PubMed).
: "Comparison of the Expression Changes after Botulinum Toxin Type A and Minocycline Administration in Lipopolysaccharide-Stimulated Rat Microglial and Astroglial Cultures." in: Frontiers in cellular and infection microbiology, Vol. 7, pp. 141, (2017) (PubMed).
: "Interleukin-18 modulation in autism spectrum disorders." in: Journal of neuroinflammation, Vol. 13, pp. 2, (2016) (PubMed).
: "Rapamycin decreases survivin expression to induce NSCLC cell apoptosis under hypoxia through inhibiting HIF-1α induction." in: Molecular biology reports, Vol. 39, Issue 1, pp. 185-91, (2011) (PubMed).
: "Interleukin-18 binding protein transgenic mice are protected against ischemic acute kidney injury." in: American journal of physiology. Renal physiology, Vol. 295, Issue 5, pp. F1414-21, (2008) (PubMed).
Aliases for IL18BP 抗体
interleukin 18 binding protein (IL18BP) 抗体interleukin 18 binding protein (Il18bp) 抗体
Igifbp 抗体
IL-18BP 抗体
IL18BP 抗体
IL18BPa 抗体
MC54L 抗体
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