IL12B 抗体
(Interleukin 12 beta (IL12B))
This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provided by RefSeq, Jul 2008].
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146 results
IL12B
适用: 人
ELISA, FACS
宿主: 兔
Monoclonal
10B1010B10
unconjugated
Recombinant Antibody
Latest Publications for our IL12B 抗体
: "CD14 knockdown reduces lipopolysaccharide-induced cell viability and expression of inflammation-associated genes in gastric cancer cells in vitro and in nude mouse xenografts." in: Molecular medicine reports, Vol. 12, Issue 3, pp. 4332-9, (2015) (PubMed).: "Effects of acupuncture on LIF and IL-12 in rats of implantation failure." in: American journal of reproductive immunology (New York, N.Y. : 1989), Vol. 67, Issue 5, pp. 383-90, (2012) (PubMed).
: "Targeting of macrophage galactose-type C-type lectin (MGL) induces DC signaling and activation." in: European journal of immunology, Vol. 42, Issue 4, pp. 936-45, (2012) (PubMed).
: "Tissue and serum markers of inflammation during the follow-up of patients with giant-cell arteritis--a prospective longitudinal study." in: Rheumatology (Oxford, England), Vol. 50, Issue 11, pp. 2061-70, (2011) (PubMed).
: "Anti-arthritis activity of cationic materials." in: Journal of cellular and molecular medicine, Vol. 14, Issue 7, pp. 2015-24, (2011) (PubMed).
: "STAT4: genetics, mechanisms, and implications for autoimmunity." in: Current allergy and asthma reports, Vol. 8, Issue 5, pp. 398-403, (2008) (PubMed).
: "Prognostic significance of the local expression of interleukin-12 in patients with advanced gastric cancer." in: Anticancer research, Vol. 28, Issue 2B, pp. 1277-83, (2008) (PubMed).
: "Distinct roles for IL-6 and IL-12p40 in mediating protection against Leishmania donovani and the expansion of IL-10+ CD4+ T cells." in: European journal of immunology, Vol. 36, Issue 7, pp. 1764-71, (2006) (PubMed).
: "The power of combinatorial immunology: IL-12 and IL-12-related dimeric cytokines in infectious diseases." in: Medical microbiology and immunology, Vol. 193, Issue 1, pp. 1-17, (2004) (PubMed).
: "Mice lacking bioactive IL-12 can generate protective, antigen-specific cellular responses to mycobacterial infection only if the IL-12 p40 subunit is present." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 3, pp. 1322-7, (2002) (PubMed).
Aliases for IL12B 抗体
interleukin 12B (IL12B) 抗体interleukin 12b (Il12b) 抗体
interleukin 12B (Il12b) 抗体
interleukin 12Ba (il12ba) 抗体
CLMF 抗体
CLMF2 抗体
CLMF p40 抗体
IL-12 抗体
IL-12 p40 抗体
IL-12.p40 抗体
IL-12B 抗体
Il-12b 抗体
Il-12p40 抗体
IL-12p40 抗体
Il12 抗体
il12b 抗体
IL12B 抗体
Il12p40 抗体
IL12p40 抗体
il12p40.b 抗体
NKSF 抗体
NKSF2 抗体
p40 抗体
zgc:152789 抗体
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