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IL-10 蛋白

(Interleukin 10 (IL10))
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011].

89 results :

IL10 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7274884
 
IL10 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7274896
 
IL10 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
产品编号 ABIN7274897
 
IL10 宿主: 人 宿主: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
产品编号 ABIN2018051
 
IL10 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant >95 % as determined by SDS-PAGE Func Active
产品编号 ABIN5509335
 
IL10 宿主: Hamster 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
产品编号 ABIN7123537
 
IL10 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
产品编号 ABIN1307664
 
IL10 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7320571
 
IL10 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7491255
 
IL10 宿主: 小鼠 Recombinant BCA
产品编号 ABIN1111705
 
IL10 宿主: 大鼠 Recombinant BCA
产品编号 ABIN1111692
 
IL10 宿主: Pig 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505464
 
IL10 宿主: 大鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505494
 
IL10 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant >95 % (SDS-PAGE)
产品编号 ABIN6253267
 
IL10 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % (SDS-PAGE) Active
产品编号 ABIN6253266
 
IL10 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505761
 
IL10 宿主: 大鼠 宿主: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
产品编号 ABIN2018048
 
IL10 宿主: 小鼠 宿主: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
产品编号 ABIN2018045
 
IL10 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
产品编号 ABIN7454147
 
IL10 宿主: 大鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 80 % as determined by SDS-PAGE Active
产品编号 ABIN7321255
 
  • 类型 Protein
    • Protein
  • 应用范围
    • SDS-PAGE (SDS)
    • ELISA
    • Western Blotting (WB)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Activity Assay (AcA)
    • Biochemical Assay (BCA)
    • Functional Studies (Func)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Cell Culture (CC)
    • Immunoprecipitation (IP)
    • Standard (STD)
  • 适用
    • Human
    • Mouse
    • Rat
    • Pig
    • Rabbit
    • Chicken
    • Cow
    • Dog
    • Cynomolgus
    • Goat
    • Guinea Pig
    • Horse
    • Rhesus Monkey
    • Baboon
    • Callithrix jacchus
    • Cat
    • Chimpanzee
    • Fox
    • Hamster
    • Llama
    • Macaca nemestrina
    • Marmota monax
    • Monkey
    • Orcinus orca
    • Red Deer
    • Sheep
    • Squirrel Monkey
    • White-eyelid mangabey (Cercocebus)
    • Zebrafish (Danio rerio)
  • 图像
  • Preservative free only
  • Carrier free only
  • 抗体来源
    • Escherichia coli (E. coli)
    • Yeast
    • HEK-293 Cells
    • CHO Cells
    • Mammalian Cells
    • Baculovirus infected Insect Cells
    • Wheat germ
  • 抗原表位
    • AA 19-178
    • AA 1-178
    • AA 19-175
    • AA 20-179
    • AA 22-175
    • full length
    • partial
    • AA 17-174
    • AA 19-164
    • AA 20-177
    • AA 20-181
    • AA 21-181
    • AA 22-178
    • AA 23-180
  • 标记
    • His tag
    • 非结合性
    • Fc Tag
    • His tag,GST tag
    • GST tag
    • His-Avi Tag
    • His-Avi Tag,Biotin
    • Myc-DYKDDDDK Tag
  • 蛋白类型
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • 生物活性
    • Biologically Active
  • Grade
    • Animal-Free
  • Supplier
    • antibodies-online
    • CUSABIO
    • Abbexa
    • Rockland
    • ProSci
    • Signalway
    • ACROBiosystems
    • Cloud-Clone
    • ITSI-Biosciences
    • OriGene

Latest Publications for our IL-10 蛋白

Phadnis-Moghe, Crawford, Kaminski: "Suppression of human B cell activation by 2,3,7,8-tetrachlorodibenzo-p-dioxin involves altered regulation of B cell lymphoma-6." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 144, Issue 1, pp. 39-50, (2015) (PubMed).

Larson, Hübner, Torrero, Morris, Brankin, Swierczewski, Davies, Vonakis, Mitre: "Chronic helminth infection reduces basophil responsiveness in an IL-10-dependent manner." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 9, pp. 4188-99, (2012) (PubMed).

Yang, Hirose, Takahashi, Kawakatsu, Takaiwa: "Recombinant protein yield in rice seed is enhanced by specific suppression of endogenous seed proteins at the same deposit site." in: Plant biotechnology journal, Vol. 10, Issue 9, pp. 1035-45, (2012) (PubMed).

Del Galdo, Wermuth, Addya, Fortina, Jimenez et al.: "NF?B activation and stimulation of chemokine production in normal human macrophages by the gadolinium-based magnetic resonance contrast agent Omniscan: possible role in the pathogenesis of ..." in: Annals of the rheumatic diseases, Vol. 69, Issue 11, pp. 2024-33, (2010) (PubMed).

van der Vliet, Wang, Yue, Koon, Balk, Exley: "Circulating myeloid dendritic cells of advanced cancer patients result in reduced activation and a biased cytokine profile in invariant NKT cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 11, pp. 7287-93, (2008) (PubMed).

Prussin, Metcalfe: "Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies." in: Journal of immunological methods, Vol. 188, Issue 1, pp. 117-28, (1996) (PubMed).

Schlaak, Schmitt, Hüls, Meyer zum Büschenfelde, Fleischer: "A sensitive and specific bioassay for the detection of human interleukin-10." in: Journal of immunological methods, Vol. 168, Issue 1, pp. 49-54, (1994) (PubMed).

Feng, Tang, Chang, Wilson: "Molecular cloning of rat cytokine synthesis inhibitory factor (IL-10) cDNA and expression in spleen and macrophages." in: Biochemical and biophysical research communications, Vol. 192, Issue 2, pp. 452-8, (1993) (PubMed).

Howard, OGarra, Ishida, de Waal Malefyt, de Vries: "Biological properties of interleukin 10." in: Journal of clinical immunology, Vol. 12, Issue 4, pp. 239-47, (1992) (PubMed).

Vieira, de Waal-Malefyt, Dang, Johnson, Kastelein, Fiorentino, deVries, Roncarolo, Mosmann, Moore: "Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 4, pp. 1172-6, (1991) (PubMed).

Aliases for IL-10 蛋白

interleukin 10 (IL10) 蛋白
interleukin 10 (Il10) 蛋白
CSIF 蛋白
GVHDS 蛋白
IL-10 蛋白
Il-10 蛋白
IL10A 蛋白
IL10X 蛋白
TGIF 蛋白
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