IKZF3 抗体
(IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012].
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66 results
IKZF3
适用: 人, 小鼠
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 350
Latest Publications for our IKZF3 抗体
: "Identification of lenalidomide resistance pathways in myeloma and targeted resensitization using cereblon replacement, inhibition of STAT3 or targeting of IRF4." in: Blood cancer journal, Vol. 9, Issue 2, pp. 19, (2019) (PubMed).: "Potent antitumor effect of combination therapy with sub-optimal doses of Akt inhibitors and pomalidomide plus dexamethasone in multiple myeloma." in: Oncology letters, Vol. 15, Issue 6, pp. 9450-9456, (2018) (PubMed).
: "p97/VCP promotes degradation of CRBN substrate glutamine synthetase and neosubstrates." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 14, pp. 3565-3571, (2017) (PubMed).
: "Activation of c-Abl Kinase Potentiates the Anti-myeloma Drug Lenalidomide by Promoting DDA1 Protein Recruitment to the CRL4 Ubiquitin Ligase." in: The Journal of biological chemistry, Vol. 292, Issue 9, pp. 3683-3691, (2017) (PubMed).
: "Selective degradation of splicing factor CAPERα by anticancer sulfonamides." in: Nature chemical biology, Vol. 13, Issue 6, pp. 675-680, (2017) (PubMed).
: "Lenalidomide increases human dendritic cell maturation in multiple myeloma patients targeting monocyte differentiation and modulating mesenchymal stromal cell inhibitory properties." in: Oncotarget, Vol. 8, Issue 32, pp. 53053-53067, (2017) (PubMed).
: "Identification of cereblon-binding proteins and relationship with response and survival after IMiDs in multiple myeloma." in: Blood, Vol. 124, Issue 4, pp. 536-45, (2014) (PubMed).
: "Ikaros family transcription factors in chronic and acute leukemia." in: American journal of hematology, Vol. 84, Issue 6, pp. 375-7, (2009) (PubMed).
: "Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits." in: Immunity, Vol. 26, Issue 3, pp. 335-44, (2007) (PubMed).
Aliases for IKZF3 抗体
IKAROS family zinc finger 3 (IKZF3) 抗体IKAROS family zinc finger 3 L homeolog (ikzf3.L) 抗体
IKAROS family zinc finger 3 (Ikzf3) 抗体
5830411O07Rik 抗体
AIO 抗体
aio 抗体
AIOLOS 抗体
aiolos 抗体
Aiolos 抗体
IKZF3 抗体
Zfpn1a3 抗体
ZNFN1A3 抗体
znfn1a3 抗体
Znfn1a3 抗体
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