IGFBP7 抗体
(Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))
This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). [provided by RefSeq, Dec 2011].
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IGFBP7
适用: 人, 大鼠, Cow, 马, 犬, 豚鼠, 兔, 猴, Bat
WB
宿主: 兔
Polyclonal
unconjugated
1 image
IGFBP7
适用: 人, 大鼠
WB, ELISA, IHC (p), IHC (fro)
宿主: 兔
Polyclonal
Biotin
Latest Publications for our IGFBP7 抗体
: "Low levels of IGFBP7 expression in high-grade serous ovarian carcinoma is associated with patient outcome." in: BMC cancer, Vol. 15, pp. 135, (2015) (PubMed).: "Stromal gene expression defines poor-prognosis subtypes in colorectal cancer." in: Nature genetics, Vol. 47, Issue 4, pp. 320-9, (2015) (PubMed).
: "Pilot study identifying myosin heavy chain 7, desmin, insulin-like growth factor 7, and annexin A2 as circulating biomarkers of human heart failure." in: Proteomics, Vol. 13, Issue 15, pp. 2324-34, (2013) (PubMed).
: "IGFBP7 binds to the IGF-1 receptor and blocks its activation by insulin-like growth factors." in: Science signaling, Vol. 5, Issue 255, pp. ra92, (2012) (PubMed).
: "Imp-L2, a putative homolog of vertebrate IGF-binding protein 7, counteracts insulin signaling in Drosophila and is essential for starvation resistance." in: Journal of biology, Vol. 7, Issue 3, pp. 10, (2008) (PubMed).
: "IGFBP7 plays a potential tumor suppressor role in colorectal carcinogenesis." in: Cancer biology & therapy, Vol. 6, Issue 3, pp. 354-9, (2007) (PubMed).
: "IGFBP7 plays a potential tumor suppressor role against colorectal carcinogenesis with its expression associated with DNA hypomethylation of exon 1." in: Journal of Zhejiang University. Science. B, Vol. 7, Issue 11, pp. 929-32, (2006) (PubMed).
Aliases for IGFBP7 抗体
insulin like growth factor binding protein 7 (IGFBP7) 抗体insulin-like growth factor binding protein 7 (igfbp7) 抗体
insulin-like growth factor binding protein 7 (Igfbp7) 抗体
insulin like growth factor binding protein 7 (Igfbp7) 抗体
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