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IFIT2 产品

(Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2))

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This gene encodes 54-kD nuclear protein that contains an arginine/serine-rich region similar to segments found in pre-mRNA splicing factors. Although the function of this protein is not yet known, structure and immunolocalization data suggest that it may play a role in pre-mRNA processing. Alternative splicing results in multiple transcript variants encoding different proteins. In addition, a pseudogene of this gene has been found on chromosome 12.[provided by RefSeq, Sep 2010].

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Featured IFIT2 Categories

IFIT2 抗体

High quality antibodies with extensive validation data.

IFIT2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IFIT2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7156667
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IP
Validations
  • (4)
Cat. No. ABIN948011
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN516833
Quantity 50 μL
Datasheet Datasheet

Recommended IFIT2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6231145
Quantity 96 tests
Datasheet Datasheet

Recommended IFIT2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307427
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3093106
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3135578
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our IFIT2 Products

Doiron, Goyon, Coyaud, Rajapakse, Raught, McBride: "The dynamic interacting landscape of MAPL reveals essential functions for SUMOylation in innate immunity." in: Scientific reports, Vol. 7, Issue 1, pp. 107, (2017) (PubMed).

Khan, Dô, Marineau, Doyon, Clément, Woodgett, Doble, Servant: "Fine-Tuning of the RIG-I-Like Receptor/Interferon Regulatory Factor 3-Dependent Antiviral Innate Immune Response by the Glycogen Synthase Kinase 3/β-Catenin Pathway." in: Molecular and cellular biology, Vol. 35, Issue 17, pp. 3029-43, (2015) (PubMed).

Feng, Wang, Ma, Yang, Liang, Zhang, Song, Li, Liu, Fan, Gao: "MicroRNA-645, up-regulated in human adencarcinoma of gastric esophageal junction, inhibits apoptosis by targeting tumor suppressor IFIT2." in: BMC cancer, Vol. 14, pp. 633, (2014) (PubMed).

Baril, Es-Saad, Chatel-Chaix, Fink, Pham, Raymond, Audette, Guenier, Duchaine, Servant, Bilodeau, Cohen, Grandvaux, Lamarre: "Genome-wide RNAi screen reveals a new role of a WNT/CTNNB1 signaling pathway as negative regulator of virus-induced innate immune responses." in: PLoS pathogens, Vol. 9, Issue 6, pp. e1003416, (2013) (PubMed).

Lee, Li, Gretz, Gebert, Dihlmann: "Absent in Melanoma 2 (AIM2) is an important mediator of interferon-dependent and -independent HLA-DRA and HLA-DRB gene expression in colorectal cancers." in: Oncogene, Vol. 31, Issue 10, pp. 1242-53, (2012) (PubMed).

van Zuylen, Doyon, Clément, Khan, DAmbrosio, Dô, St-Amant-Verret, Wissanji, Emery, Gingras, Meloche, Servant: "Proteomic profiling of the TRAF3 interactome network reveals a new role for the ER-to-Golgi transport compartments in innate immunity." in: PLoS pathogens, Vol. 8, Issue 7, pp. e1002747, (2012) (PubMed).

Terenzi, Hui, Merrick, Sen: "Distinct induction patterns and functions of two closely related interferon-inducible human genes, ISG54 and ISG56." in: The Journal of biological chemistry, Vol. 281, Issue 45, pp. 34064-71, (2006) (PubMed).

Synonyms and alternative names related to IFIT2

interferon induced protein with tetratricopeptide repeats 2 (IFIT2), interferon-induced protein with tetratricopeptide repeats 2 (Ifit2), interferon-induced protein with tetratricopeptide repeats 15 (ifit15), interferon induced protein with tetratricopeptide repeats 2 (Ifit2), AV302338, cig42, DKFZp468G198, G10P2, GARG-39, IFI-54, IFI-54K, IFI54, Ifi54, IFIT-2, ISG-54 K, ISG-54K, ISG54, P54, wu:fb58d07

Protein level used designations for IFIT2

  • Interferon, alpha-inducible protein (MW 54kD)
  • interferon-induced 54 kDa protein
  • interferon-induced protein 54
  • interferon-induced protein with tetratricopeptide repeats 2
  • GARG-39
  • IFI-54K
  • IFIT-2
  • glucocorticoid-attenuated response gene 39 protein
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