IDO 抗体
(Indoleamine 2,3-Dioxygenase (IDO))
This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011].
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Latest Publications for our IDO 抗体
: "Investigation of the aryl hydrocarbon receptor and the intrinsic tumoral component of the kynurenine pathway of tryptophan metabolism in primary brain tumors." in: Journal of neuro-oncology, Vol. 139, Issue 2, pp. 239-249, (2019) (PubMed).: "Tryptophan PET Imaging of the Kynurenine Pathway in Patient-Derived Xenograft Models of Glioblastoma." in: Molecular imaging, Vol. 15, (2016) (PubMed).
: "Molecular imaging correlates of tryptophan metabolism via the kynurenine pathway in human meningiomas." in: Neuro-oncology, Vol. 17, Issue 9, pp. 1284-92, (2015) (PubMed).
: "Granuloma correlates of protection against tuberculosis and mechanisms of immune modulation by Mycobacterium tuberculosis." in: The Journal of infectious diseases, Vol. 207, Issue 7, pp. 1115-27, (2013) (PubMed).
: "Live-attenuated lentivirus immunization modulates innate immunity and inflammation while protecting rhesus macaques from vaginal simian immunodeficiency virus challenge." in: Journal of virology, Vol. 86, Issue 17, pp. 9188-200, (2012) (PubMed).
: "Plasmacytoid dendritic cells prevent cigarette smoke and Chlamydophila pneumoniae-induced Th2 inflammatory responses." in: American journal of respiratory cell and molecular biology, Vol. 43, Issue 4, pp. 422-31, (2010) (PubMed).
: "Immunotherapeutic suppression of indoleamine 2,3-dioxygenase and tumor growth with ethyl pyruvate." in: Cancer research, Vol. 70, Issue 5, pp. 1845-53, (2010) (PubMed).
: "Indoleamine 2,3-dioxygenase tissue distribution and cellular localization in mice: implications for its biological functions." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 58, Issue 1, pp. 17-28, (2009) (PubMed).
: "Expression of indoleamine 2,3-dioxygenase in the rhesus monkey and common marmoset." in: Journal of reproductive immunology, Vol. 78, Issue 2, pp. 125-33, (2008) (PubMed).
: "Deficiency of indoleamine 2,3-dioxygenase enhances commensal-induced antibody responses and protects against Citrobacter rodentium-induced colitis." in: Infection and immunity, Vol. 76, Issue 7, pp. 3045-53, (2008) (PubMed).
Aliases for IDO 抗体
indoleamine 2,3-dioxygenase 1 (IDO1) 抗体indoleamine 2,3-dioxygenase 1 (Ido1) 抗体
IDO 抗体
Ido 抗体
IDO-1 抗体
INDO 抗体
Indo 抗体
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