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IDH3B 产品

(Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B))

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Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

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Featured IDH3B Categories

IDH3B 抗体

High quality antibodies with extensive validation data.

IDH3B 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IDH3B 抗体

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Reactivity
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  • (3)
Cat. No. ABIN768560
Quantity 100 μg
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Cat. No. ABIN6142149
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Cat. No. ABIN7129804
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Cat. No. ABIN1307376
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Cat. No. ABIN3081729
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Latest Publications for our IDH3B Products

Bzymek, Colman: "Role of alpha-Asp181, beta-Asp192, and gamma-Asp190 in the distinctive subunits of human NAD-specific isocitrate dehydrogenase." in: Biochemistry, Vol. 46, Issue 18, pp. 5391-7, (2007) (PubMed).

Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: "The DNA sequence and comparative analysis of human chromosome 20. ..." in: Nature, Vol. 414, Issue 6866, pp. 865-71, (2002) (PubMed).

Kim, Koh, Kim, Jo, Huh, Jeong, Lee, Song, Huh: "Identification and functional characterization of a novel, tissue-specific NAD(+)-dependent isocitrate dehydrogenase beta subunit isoform." in: The Journal of biological chemistry, Vol. 274, Issue 52, pp. 36866-75, (2000) (PubMed).

Synonyms and alternative names related to IDH3B

isocitrate dehydrogenase 3 (NAD(+)) beta (IDH3B), isocitrate dehydrogenase 3 (NAD+) beta (Idh3B), isocitrate dehydrogenase 3 (NAD+) beta (Idh3b), isocitrate dehydrogenase 3 (NAD+) beta (idh3b), isocitrate dehydrogenase 3 (NAD+) beta S homeolog (idh3b.S), isocitrate dehydrogenase 3 (NAD(+)) beta (Idh3b), C78231, H-IDHB, IDH1, IDH3, MGC79028, RP46, zgc:86647

Protein level used designations for IDH3B

  • NAD(+)-specific ICDH subunit beta
  • NAD+-specific ICDH
  • NAD+-specific isocitrate dehydrogenase b subunit
  • NAD+-specific isocitrate dehydrogenase beta
  • isocitrate dehydrogenase [NAD] subunit beta, mitochondrial
  • isocitrate dehydrogenase, NAD(+)-specific, mitochondrial, beta subunit
  • isocitric dehydrogenase subunit beta
  • N14A tumor-related protein
  • isocitrate dehydrogenase 3 beta
  • isocitrate dehydrogenase 3, beta subunit
  • isocitrate dehydrogenase 3 (NAD+) beta
  • NAD(+)-dependent isocitrate dehydrogenase subunit 3
  • NAD(+)-isocitrate dehydrogenase subunit 1
  • mitochondrial NAD+isocitrate dehydrogenase 3 beta variant 2
  • isocitrate dehydrogenase [NAD] subunit beta, mitochondrial-like
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