IDH3A 抗体
(Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A))
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. [provided by RefSeq, Jul 2008].
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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Cat. No.
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Quantity
100 μg
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Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
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WB, IHC
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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Datasheet
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Application
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Cat. No.
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Quantity
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Datasheet
Application
WB, IHC, IHC (p)
Validations
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Cat. No.
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Quantity
100 μL
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Datasheet
Reactivity
Cow, Human, Monkey, Mouse, Rat
Application
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- (2)
Cat. No.
ABIN7303678
Quantity
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Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN751545
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, IF (cc), IF (p)
Validations
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Quantity
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Datasheet
Datasheet
Latest Publications for our IDH3A 抗体
: "Metabolic reprogramming of cancer-associated fibroblasts by IDH3? downregulation." in: Cell reports, Vol. 10, Issue 8, pp. 1335-48, (2015) (PubMed).: "Proteomic identification of mitochondrial targets involved in andrographolide sodium bisulfite-induced nephrotoxicity in a rat model." in: Environmental toxicology and pharmacology, Vol. 40, Issue 2, pp. 592-9, (2015) (PubMed).
: "Loss of the respiratory enzyme citrate synthase directly links the Warburg effect to tumor malignancy." in: Scientific reports, Vol. 2, pp. 785, (2012) (PubMed).
: "Evaluation by mutagenesis of the importance of 3 arginines in alpha, beta, and gamma subunits of human NAD-dependent isocitrate dehydrogenase." in: The Journal of biological chemistry, Vol. 278, Issue 52, pp. 52146-53, (2003) (PubMed).
: "Identification and functional characterization of a novel, tissue-specific NAD(+)-dependent isocitrate dehydrogenase beta subunit isoform." in: The Journal of biological chemistry, Vol. 274, Issue 52, pp. 36866-75, (2000) (PubMed).
: "Bovine NAD+-dependent isocitrate dehydrogenase: alternative splicing and tissue-dependent expression of subunit 1." in: Biochemistry, Vol. 39, Issue 7, pp. 1807-16, (2000) (PubMed).
Aliases for IDH3A 抗体
isocitrate dehydrogenase 3 (NAD+) alpha (idh3a) 抗体isocitrate dehydrogenase 3 (NAD(+)) alpha (IDH3A) 抗体
isocitrate dehydrogenase 3 (NAD(+)) alpha (idh3a) 抗体
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