HTRA3 抗体
(HtrA Serine Peptidase 3 (HTRA3))
Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM) proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1. Inhibits signaling mediated by TGF-beta family proteins possibly indirectly by degradation of these ECM proteoglycans (By similarity). May act as a tumor suppressor. Negatively regulates, in vitro, trophoblast invasion during placental development and may be involved in the development of the placenta in vivo. May also have a role in ovarian development, granulosa cell differentiation and luteinization (By similarity).
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Latest Publications for our HTRA3 抗体
: "High temperature requirement A3 (HtrA3) promotes etoposide- and cisplatin-induced cytotoxicity in lung cancer cell lines." in: The Journal of biological chemistry, Vol. 285, Issue 16, pp. 12011-27, (2010) (PubMed).: "Changes in mRNA and protein levels of human HtrA1, HtrA2 and HtrA3 in ovarian cancer." in: Clinical biochemistry, Vol. 41, Issue 7-8, pp. 561-9, (2008) (PubMed).
: "Implications of the serine protease HtrA1 in amyloid precursor protein processing." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 17, pp. 6021-6, (2005) (PubMed).
: "Identification and cloning of two isoforms of human high-temperature requirement factor A3 (HtrA3), characterization of its genomic structure and comparison of its tissue distribution with HtrA1 and ..." in: The Biochemical journal, Vol. 371, Issue Pt 1, pp. 39-48, (2003) (PubMed).
Aliases for HTRA3 抗体
Trypsin-like serine protease (htrA3) 抗体HtrA serine peptidase 3 (HTRA3) 抗体
HtrA serine peptidase 3 (Htra3) 抗体
2210021K23Rik 抗体
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