The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN). [provided by RefSeq, Oct 2008].
custom-made
HSPB1
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, SDS, WB
custom-made
HSPB1
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, SDS, WB
Conway, Nafar, Straka, Mearow: "Modulation of amyloid-β protein precursor expression by HspB1." in: Journal of Alzheimer's disease : JAD, Vol. 42, Issue 2, pp. 435-50, (2014) (PubMed).
Zhao, Wang, Wang, Zhang, Li, Su, Zhou, Yu, Liu: "Pan-amyloid oligomer specific scFv antibody attenuates memory deficits and brain amyloid burden in mice with Alzheimer's disease." in: Current Alzheimer research, Vol. 11, Issue 1, pp. 69-78, (2014) (PubMed).
Imami, Bhavsar, Yu, Brown, Rogers, Finlay, Foster: "Global impact of Salmonella pathogenicity island 2-secreted effectors on the host phosphoproteome." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 6, pp. 1632-43, (2013) (PubMed).
Iizuka, Okamoto, Matsushita, Kimura, Nagai, Arito, Kurokawa, Masuko, Suematsu, Hirohata, Kato: "Identification of autoantigens specific for systemic lupus erythematosus with central nervous system involvement." in: Lupus, Vol. 19, Issue 6, pp. 717-26, (2010) (PubMed).
Aliases for HSP27 蛋白
heat shock protein family B (small) member 1 (HSPB1) 蛋白 heat shock protein 1 (Hspb1) 蛋白 heat shock protein family B (small) member 1 (Hspb1) 蛋白 heat shock protein, alpha-crystallin-related, 1 (hspb1) 蛋白 heat shock protein family B (small) member 1 L homeolog (hspb1.L) 蛋白 heat shock protein family B (small) member 1 (hspb1) 蛋白 27kDa 蛋白 cb153 蛋白 cb660 蛋白 CMT2F 蛋白 cmt2f 蛋白 HMN2B 蛋白 HS.76067 蛋白 hs.76067 蛋白 hsp1 蛋白 Hsp25 蛋白 hsp25 蛋白 HSP27 蛋白 Hsp27 蛋白 hsp27 蛋白 HSP28 蛋白 hsp28 蛋白 HSPB1 蛋白 id:ibd2821 蛋白 sb:cb660 蛋白 SRP27 蛋白 zgc:103437 蛋白