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HRK 产品

(Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))

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This gene encodes a member of the BCL-2 protein family. Members of this family are involved in activating or inhibiting apoptosis. The encoded protein localizes to intracellular membranes. This protein promotes apoptosis by interacting with the apoptotic inhibitors BCL-2 and BCL-X(L) via its BH3 domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012].

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Featured HRK Categories

HRK 抗体

High quality antibodies with extensive validation data.

HRK ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Recommended HRK 抗体

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Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
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  • (3)
  • (1)
Cat. No. ABIN2474088
Quantity 50 μg
Datasheet Datasheet
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Cat. No. ABIN7243397
Quantity 200 μL
Datasheet Datasheet
Reactivity Mouse, Rat
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Cat. No. ABIN2559409
Quantity 100 μL
Datasheet Datasheet

Recommended HRK ELISA试剂盒

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Reactivity
Analytical Method
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Cat. No.
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Quantity 96 tests
Datasheet Datasheet
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Analytical Method
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Cat. No. ABIN1120326
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Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1120327
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Recommended HRK 蛋白

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Latest Publications for our HRK Products

Lucas, Milani, Butterworth, Carmell, Scott, Clark, Cohen, Varadarajan: "High CIP2A levels correlate with an antiapoptotic phenotype that can be overcome by targeting BCL-XL in chronic myeloid leukemia." in: Leukemia, Vol. 30, Issue 6, pp. 1273-81, (2016) (PubMed).

Conery, Centore, Spillane, Follmer, Bommi-Reddy, Hatton, Bryant, Greninger, Amzallag, Benes, Mertz, Sims: "Preclinical Anticancer Efficacy of BET Bromodomain Inhibitors Is Determined by the Apoptotic Response." in: Cancer research, Vol. 76, Issue 6, pp. 1313-9, (2016) (PubMed).

Nakamura, Ishida, Shimada, Nakase, Sakaki, Konishi: "Frequent HRK inactivation associated with low apoptotic index in secondary glioblastomas." in: Acta neuropathologica, Vol. 110, Issue 4, pp. 402-10, (2005) (PubMed).

Sunayama, Ando, Itoh, Tomiyama, Sakurada, Sugiyama, Kang, Tashiro, Gotoh, Kuchino, Kitanaka: "Physical and functional interaction between BH3-only protein Hrk and mitochondrial pore-forming protein p32." in: Cell death and differentiation, Vol. 11, Issue 7, pp. 771-81, (2004) (PubMed).

Wakabayashi, Kosaka, Hommura: "Up-regulation of Hrk, a regulator of cell death, in retinal ganglion cells of axotomized rat retina." in: Neuroscience letters, Vol. 318, Issue 2, pp. 77-80, (2002) (PubMed).

Sanz, Mellstrom, Link, Naranjo, Fernandez-Luna: "Interleukin 3-dependent activation of DREAM is involved in transcriptional silencing of the apoptotic Hrk gene in hematopoietic progenitor cells." in: The EMBO journal, Vol. 20, Issue 9, pp. 2286-92, (2001) (PubMed).

Lockshin, Osborne, Zakeri: "Cell death in the third millennium." in: Cell death and differentiation, Vol. 7, Issue 1, pp. 2-7, (2000) (PubMed).

Synonyms and alternative names related to HRK

harakiri, BCL2 interacting protein (HRK), harakiri, BCL2 interacting protein (contains only BH3 domain) (Hrk), harakiri, BCL2 interacting protein (Hrk), AI838259, Bid3, DP5, Dp5, HARAKIRI, harakiri

Protein level used designations for HRK

  • BCL2-interacting protein
  • BH3-interacting domain-containing protein 3
  • activator of apoptosis Hrk
  • activator of apoptosis harakiri
  • death protein 5
  • neuronal death protein DP5
  • BH3 interacting (with BCL2 family) domain, apoptosis agonist
  • BH3 interacting domain 3
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