HOXA9 产品
(Homeobox A9 (HOXA9))
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In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is highly similar to the abdominal-B (Abd-B) gene of Drosophila. A specific translocation event which causes a fusion between this gene and the NUP98 gene has been associated with myeloid leukemogenesis. Read-through transcription exists between this gene and the upstream homeobox A10 (HOXA10) gene.[provided by RefSeq, Mar 2011].
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Latest Publications for our HOXA9 Products
: "The histone chaperone NAP1L3 is required for haematopoietic stem cell maintenance and differentiation." in: Scientific reports, Vol. 8, Issue 1, pp. 11202, (2019) (PubMed).: "Upregulated HOXA9 expression is associated with lymph node metastasis in colorectal cancer." in: Oncology letters, Vol. 15, Issue 3, pp. 2756-2762, (2018) (PubMed).
: "Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia. ..." in: Cancer cell, Vol. 31, Issue 4, pp. 549-562.e11, (2017) (PubMed).
: "Gene expression comparison reveals distinct basal expression of HOX members and differential TNF-induced response between brain- and spinal cord-derived microvascular endothelial cells." in: Journal of neuroinflammation, Vol. 13, Issue 1, pp. 290, (2016) (PubMed).
: "Transcriptional profiling of HOXA9-regulated genes in human glioblastoma cell models." in: Genomics data, Vol. 5, pp. 54-8, (2015) (PubMed).
: "Homeobox A9 directly targeted by miR-196b regulates aggressiveness through nuclear Factor-kappa B activity in non-small cell lung cancer cells." in: Molecular carcinogenesis, Vol. 55, Issue 12, pp. 1915-1926, (2015) (PubMed).
: "A transcriptomic signature mediated by HOXA9 promotes human glioblastoma initiation, aggressiveness and resistance to temozolomide." in: Oncotarget, Vol. 6, Issue 10, pp. 7657-74, (2015) (PubMed).
: "HOXA9 promotes homotypic and heterotypic cell interactions that facilitate ovarian cancer dissemination via its induction of P-cadherin." in: Molecular cancer, Vol. 13, pp. 170, (2014) (PubMed).
: "BRCA1 is a negative modulator of the PRC2 complex." in: The EMBO journal, Vol. 32, Issue 11, pp. 1584-97, (2013) (PubMed).
: "An MLL-dependent network sustains hematopoiesis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 29, pp. 12000-5, (2013) (PubMed).
Synonyms and alternative names related to HOXA9
homeobox A9 (HOXA9), homeobox protein Hox-A9 (LOC745701), homeobox A9 (hoxa9), homeobox A9 S homeolog (hoxa9.S), homeobox A9 (Hoxa9), homeobox A7 (Hoxa7), ABD-B, D6a9, Hox-1.7, HOX1, HOX1.7, HOX1G, Hox1r5, HOXA-9, Hoxa7, HOXA9, hoxa9-A, xhoxa9, XlHbox-6, XlHbox6Protein level used designations for HOXA9
- homeobox A9
- homeobox protein Hox-A9
- HOXA9A
- XIHbox 6
- homeobox protein Hox-1G
- homeodomain protein HOXA9
- homeo box A9
- homeobox protein Hox-1.7
- Homeobox gene A7
- homeobox protein Hox-1.1
- homeobox protein Hox-A7
- homeobox protein R5
- hox-1.1
- homeobox protein A9
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