This gene encodes a HORMA domain-containing protein. HORMA domains are involved in chromatin binding and play a role in cell cycle regulation. The encoded protein may play a role in meiosis, and expression of this gene is a potential marker for cancer. A pseudogene of this gene is located on the long arm of chromosome 6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010].
Watkins, Weekes, Shah, Gazinska, Joshi, Sidhu, Gillett, Pinder, Vanoli, Jasin, Mayrhofer, Isaksson, Cheang, Mirza, Frankum, Lord, Ashworth, Vinayak, Ford, Telli, Grigoriadis, Tutt: "Genomic Complexity Profiling Reveals That HORMAD1 Overexpression Contributes to Homologous Recombination Deficiency in Triple-Negative Breast Cancers." in: Cancer discovery, Vol. 5, Issue 5, pp. 488-505, (2015) (PubMed).
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).
Aliases for HORMAD1 抗体
HORMA domain containing 1 (HORMAD1) 抗体 HORMA domain containing 1 (Hormad1) 抗体 HORMA domain containing 1 (hormad1) 抗体 HORMA domain containing 1 S homeolog (hormad1.S) 抗体 4921522K05Rik 抗体 CT46 抗体 HORMAD1 抗体 NOHMA 抗体 Nohma 抗体 RGD1564960 抗体 zgc:92129 抗体