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HMGCR 蛋白

(3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))
HMG-CoA reductase is the rate-limiting enzyme for cholesterol synthesis and is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from mevalonate, the product of the reaction catalyzed by reductase. Normally in mammalian cells this enzyme is suppressed by cholesterol derived from the internalization and degradation of low density lipoprotein (LDL) via the LDL receptor. Competitive inhibitors of the reductase induce the expression of LDL receptors in the liver, which in turn increases the catabolism of plasma LDL and lowers the plasma concentration of cholesterol, an important determinant of atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].

9 results :

custom-made HMGCR 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7563576
 
custom-made HMGCR 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7554104
 
HMGCR 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
产品编号 ABIN7121607
 
HMGCR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
产品编号 ABIN1306814
 
HMGCR 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant WB, SDS, ELISA
产品编号 ABIN7577438
 
HMGCR 宿主: 大鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 97 % WB, SDS, Imm, PC
产品编号 ABIN7397588
 
custom-made HMGCR 宿主: 小鼠 宿主: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, SDS, ELISA
产品编号 ABIN3134765
 
custom-made HMGCR 宿主: 人 宿主: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, SDS, ELISA
产品编号 ABIN3111788
 
HMGCR 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % SDS
产品编号 ABIN5709669
 
  • 类型 Protein
    • Protein
  • 应用范围
    • Western Blotting (WB)
    • ELISA
    • SDS-PAGE (SDS)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Immunogen (Imm)
    • Positive Control (PC)
  • 适用
    • Human
    • Mouse
    • Rat
  • 图像
  • Carrier free only
  • 抗体来源
    • Escherichia coli (E. coli)
    • Cell-free protein synthesis (CFPS)
    • HEK-293 Cells
    • Wheat germ
  • 抗原表位
    • AA 1-887
    • AA 1-888
    • AA 1-835
    • AA 588-887
    • AA 638-887
    • AA 700-860
    • partial
  • 标记
    • His tag
    • Strep Tag
    • GST tag
    • SUMO Tag
  • 蛋白类型
    • Recombinant
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • custom-made
  • Supplier
    • antibodies-online
    • Signalway

Aliases for HMGCR 蛋白

3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) 蛋白
3-hydroxy-3-methylglutaryl-CoA reductase L homeolog (hmgcr.L) 蛋白
3-hydroxy-3-methylglutaryl-Coenzyme A reductase (Hmgcr) 蛋白
3-hydroxy-3-methylglutaryl-CoA reductase (Hmgcr) 蛋白
HMG Coenzyme A reductase (Hmgcr) 蛋白
3-hydroxy-3-methylglutaryl-CoA reductase b (hmgcrb) 蛋白
3H3M 蛋白
BcDNA:LD15354 蛋白
bro1 蛋白
bs32f05.y1 蛋白
CG10367 蛋白
Clb 蛋白
clb 蛋白
Dmel\\CG10367 蛋白
DmHMG-CoAr 蛋白
Hmg 蛋白
hmg-coa-r 蛋白
HMG-CoAR 蛋白
HmG-CoAR 蛋白
hmgc 蛋白
HMGCoAR 蛋白
HMGCoAr 蛋白
HMGCoARr 蛋白
HMGCR 蛋白
hmgcr 蛋白
hmgcr2 蛋白
HMGCR_Dm 蛋白
HMGR 蛋白
hmgrc 蛋白
im:6912716 蛋白
l(3)01152 蛋白
l(3)04684 蛋白
LDLCQ3 蛋白
Red 蛋白
zgc:110746 蛋白
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