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HIST2H3A 产品

(Histone Cluster 2, H3a (HIST2H3A))

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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.

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Featured HIST2H3A Categories

HIST2H3A 抗体

High quality antibodies with extensive validation data.

HIST2H3A 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HIST2H3A 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (8)
Cat. No. ABIN7439000
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7155429
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (5)
  • (1)
Cat. No. ABIN1881419
Quantity 400 μL
Datasheet Datasheet

Recommended HIST2H3A ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956567
Quantity 96 tests
Datasheet Datasheet

Recommended HIST2H3A 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306711
Quantity 25 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7417540
Quantity 100 μg
Datasheet Datasheet
Reactivity Chicken
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7417543
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our HIST2H3A Products

Neumann, Hancock, Buning, Routh, Chapman, Somers, Owen-Hughes, van Noort, Rhodes, Chin: "A method for genetically installing site-specific acetylation in recombinant histones defines the effects of H3 K56 acetylation." in: Molecular cell, Vol. 36, Issue 1, pp. 153-63, (2009) (PubMed).

Hurd, Bannister, Halls, Dawson, Vermeulen, Olsen, Ismail, Somers, Mann, Owen-Hughes, Gout, Kouzarides: "Phosphorylation of histone H3 Thr-45 is linked to apoptosis." in: The Journal of biological chemistry, Vol. 284, Issue 24, pp. 16575-83, (2009) (PubMed).

Yuan, Pu, Zhang, Lou: "Histone H3-K56 acetylation is important for genomic stability in mammals." in: Cell cycle (Georgetown, Tex.), Vol. 8, Issue 11, pp. 1747-53, (2009) (PubMed).

Chang, Zhang, Beezhold, Bhatia, Zhao, Chen, Castranova, Shi, Chen: "Sustained JNK1 activation is associated with altered histone H3 methylations in human liver cancer." in: Journal of hepatology, Vol. 50, Issue 2, pp. 323-33, (2009) (PubMed).

Kobza, Sarath, Zempleni: "Prokaryotic BirA ligase biotinylates K4, K9, K18 and K23 in histone H3." in: BMB reports, Vol. 41, Issue 4, pp. 310-5, (2008) (PubMed).

Synonyms and alternative names related to HIST2H3A

histone cluster 2 H3 family member a (HIST2H3A), H3/n, H3/o

Protein level used designations for HIST2H3A

  • histone 2, H3a
  • histone H3.2
  • histone H3/o
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