HIP1 产品
(Huntingtin Interacting Protein 1 (HIP1))
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The product of this gene is a membrane-associated protein that colocalizes with huntingtin. This protein has similarities to cytoskeleton proteins and its interaction with huntingtin is thought to play a functional role in the cell filament network. Loss of normal huntingtin-HIP1 interaction in Huntington disease may contribute to a defect in membrane-cytoskeletal integrity in the brain. This gene could help in the understanding of the normal function of huntingtin and also the pathogenesis of Huntington disease. It also has been implicated in the pathogenesis of hematopoietic malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].
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Featured HIP1 Categories
HIP1 抗体
High quality antibodies with extensive validation data.
HIP1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
HIP1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HIP1 抗体
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Cat. No.
ABIN561263
Quantity
100 μg
Datasheet
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Cat. No.
ABIN7155937
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Cat. No.
ABIN7262825
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Recommended HIP1 ELISA试剂盒
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ABIN6967472
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Cat. No.
ABIN6956610
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Recommended HIP1 蛋白
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ABIN1306634
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10 μg
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Cat. No.
ABIN1306636
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Reactivity
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Latest Publications for our HIP1 Products
: "Clathrin light chains are required for the gyrating-clathrin recycling pathway and thereby promote cell migration." in: Nature communications, Vol. 5, pp. 3891, (2014) (PubMed).: "Replacement of charged and polar residues in the coiled-coiled interface of huntingtin-interacting protein 1 (HIP1) causes aggregation and cell death." in: FEBS letters, Vol. 586, Issue 19, pp. 3030-6, (2012) (PubMed).
: "Identification of HYPK-interacting proteins reveals involvement of HYPK in regulating cell growth, cell cycle, unfolded protein response and cell death." in: PLoS ONE, Vol. 7, Issue 12, pp. e51415, (2012) (PubMed).
: "G protein-coupled receptor kinase 5 phosphorylation of hip regulates internalization of the chemokine receptor CXCR4." in: Biochemistry, Vol. 50, Issue 32, pp. 6933-41, (2011) (PubMed).
: "Regulation of RE1 protein silencing transcription factor (REST) expression by HIP1 protein interactor (HIPPI)." in: The Journal of biological chemistry, Vol. 286, Issue 39, pp. 33759-69, (2011) (PubMed).
: "Genome wide gene expression regulation by HIP1 Protein Interactor, HIPPI: prediction and validation." in: BMC genomics, Vol. 12, pp. 463, (2011) (PubMed).
: "Transcription regulation of caspase-1 by R393 of HIPPI and its molecular partner HIP-1." in: Nucleic acids research, Vol. 38, Issue 3, pp. 878-92, (2010) (PubMed).
: "Huntingtin interacting protein 1 is a novel brain tumor marker that associates with epidermal growth factor receptor." in: Cancer research, Vol. 67, Issue 8, pp. 3609-15, (2007) (PubMed).
: "Aberrant Huntingtin interacting protein 1 in lymphoid malignancies." in: Cancer research, Vol. 67, Issue 18, pp. 8923-31, (2007) (PubMed).
: "The T-box transcription factor T-bet in immunity and autoimmunity." in: Cellular & molecular immunology, Vol. 3, Issue 2, pp. 87-95, (2006) (PubMed).
Synonyms and alternative names related to HIP1
huntingtin interacting protein 1 (HIP1), Huntingtin interacting protein 1 (Hip1), huntingtin interacting protein 1 (Hip1), huntingtin interacting protein 1 (hip1), 2610109B09Rik, A930014B11Rik, CG10971, Dmel\\CG10971, E130315I21Rik, HIP-I, Hip1R, ILWEQ, mKIAA4113Protein level used designations for HIP1
- huntingtin-interacting protein 1
- huntingtin-interacting protein I
- CG10971-PA
- CG10971-PB
- Hip1-PA
- Hip1-PB
- huntingtin interacting protein 1
- HIP-I
- LOW QUALITY PROTEIN: huntingtin-interacting protein 1
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