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Sonic Hedgehog ELISA试剂盒

(Sonic Hedgehog (SHH))
This gene encodes a protein that is instrumental in patterning the early embryo. It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. Of three human proteins showing sequence and functional similarity to the sonic hedgehog protein of Drosophila, this protein is the most similar. The protein is made as a precursor that is autocatalytically cleaved\; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the developing embryo. Defects in this protein or in its signalling pathway are a cause of holoprosencephaly (HPE), a disorder in which the developing forebrain fails to correctly separate into right and left hemispheres. HPE is manifested by facial deformities. It is also thought that mutations in this gene or in its signalling pathway may be responsible for VACTERL syndrome, which is characterized by vertebral defects, anal atresia, tracheoesophageal fistula with esophageal atresia, radial and renal dysplasia, cardiac anomalies, and limb abnormalities. Additionally, mutations in a long range enhancer located approximately 1 megabase upstream of this gene disrupt limb patterning and can result in preaxial polydactyly. [provided by RefSeq, Jul 2008].
Sonic Hedgehog ELISA 试剂盒 Sonic Hedgehog ELISA 试剂盒 Sonic Hedgehog ELISA 试剂盒 (ABIN6730870)

SHH 适用: 人 Colorimetric Sandwich ELISA 78 pg/mL - 5000 pg/mL Cell Lysate, Tissue Homogenate

Sonic Hedgehog ELISA 试剂盒 Sonic Hedgehog ELISA 试剂盒 Sonic Hedgehog ELISA 试剂盒 (ABIN6574290)

SHH 适用: 大鼠 Colorimetric Sandwich ELISA 1.56 ng/mL - 100 ng/mL Cell Lysate, Tissue Homogenate

Sonic Hedgehog ELISA 试剂盒 Sonic Hedgehog ELISA 试剂盒 Sonic Hedgehog ELISA 试剂盒 (ABIN6975108)

SHH 适用: 小鼠 Colorimetric Sandwich ELISA 28 pg/mL - 1800 pg/mL Cell Lysate, Plasma, Serum, Tissue Homogenate

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Popular Sonic Hedgehog ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
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Validations
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Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (5)
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Quantity 96 tests
Datasheet Datasheet
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Validations
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Quantity 96 tests
Datasheet Datasheet
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Validations
  • (1)
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Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
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Quantity 96 tests
Datasheet Datasheet
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Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
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Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
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Quantity 96 tests
Datasheet Datasheet
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Quantity 96 tests
Datasheet Datasheet
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Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
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Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN625425
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN585299
Quantity 96 tests
Datasheet Datasheet
Reactivity Chicken
Analytical Method Competition ELISA
Validations
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Quantity 96 tests
Datasheet Datasheet
Reactivity Chicken
Analytical Method
Validations
Cat. No. ABIN1159119
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6385197
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative DNA-Binding ELISA
Validations
Cat. No. ABIN6730851
Quantity 96 tests
Datasheet Datasheet

Latest Publications for our Sonic Hedgehog ELISA试剂盒

Beyer, Huscher, Ramming, Bergmann, Avouac, Guiducci, Meier, Vettori, Siegert, Jaeger, Maurer, Riemekasten, Walker, Müller-Ladner, Valentini, Matucci-Cerinic, Allanore, Distler, Schett, Distler: "Elevated serum levels of sonic hedgehog are associated with fibrotic and vascular manifestations in systemic sclerosis." in: Annals of the rheumatic diseases, Vol. 77, Issue 4, pp. 626-628, (2019) (PubMed).

Halepoto, Bashir, Zeina, Al-Ayadhi: "Correlation Between Hedgehog (Hh) Protein Family and Brain-Derived Neurotrophic Factor (BDNF) in Autism Spectrum Disorder (ASD)." in: Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, Vol. 25, Issue 12, pp. 882-5, (2016) (PubMed).

Li, Han, Lin, He, Yu, Zhao: "Hair Growth Promotion Activity and Its Mechanism of Polygonum multiflorum." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 517901, (2015) (PubMed).

Al-Ayadhi: "Relationship between Sonic hedgehog protein, brain-derived neurotrophic factor and oxidative stress in autism spectrum disorders." in: Neurochemical research, Vol. 37, Issue 2, pp. 394-400, (2012) (PubMed).

Cigna, Farrokhi Moshai, Brayer, Marchal-Somme, Wémeau-Stervinou, Fabre, Mal, Lesèche, Dehoux, Soler, Crestani, Mailleux: "The hedgehog system machinery controls transforming growth factor-?-dependent myofibroblastic differentiation in humans: involvement in idiopathic pulmonary fibrosis." in: The American journal of pathology, Vol. 181, Issue 6, pp. 2126-37, (2012) (PubMed).

Filges, Röthlisberger, Blattner, Boesch, Demougin, Wenzel, Huber, Heinimann, Weber, Miny: "Deletion in Xp22.11: PTCHD1 is a candidate gene for X-linked intellectual disability with or without autism." in: Clinical genetics, Vol. 79, Issue 1, pp. 79-85, (2011) (PubMed).

Aliases for Sonic Hedgehog ELISA试剂盒

sonic hedgehog (SHH) ELISA试剂盒
sonic hedgehog (Shh) ELISA试剂盒
sonic hedgehog a (shha) ELISA试剂盒
sonic hedgehog L homeolog (shh.L) ELISA试剂盒
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sonic hedgehog protein A (shh) ELISA试剂盒
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