HBEGF 抗体
(Heparin-Binding EGF-Like Growth Factor (HBEGF))
Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.
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Latest Publications for our HBEGF 抗体
: "Eckol Alleviates Intestinal Dysfunction during Suckling-to-Weaning Transition via Modulation of PDX1 and HBEGF." in: International journal of molecular sciences, Vol. 21, Issue 13, (2020) (PubMed).: "CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors. ..." in: Nature communications, Vol. 8, Issue 1, pp. 286, (2018) (PubMed).
: "Heterogeneity of Notch signaling in astrocytes and the effects of GFAP and vimentin deficiency." in: Journal of neurochemistry, (2015) (PubMed).
: "Evaluation of the BDCA2-DTR Transgenic Mouse Model in Chronic and Acute Inflammation." in: PLoS ONE, Vol. 10, Issue 8, pp. e0134176, (2015) (PubMed).
: "Heparin-binding EGF-like growth factor is a promising target for ovarian cancer therapy." in: Cancer research, Vol. 64, Issue 16, pp. 5720-7, (2004) (PubMed).
: "EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF." in: Nature, Vol. 402, Issue 6764, pp. 884-8, (2000) (PubMed).
: "Heparin-binding EGF-like growth factor, which acts as the diphtheria toxin receptor, forms a complex with membrane protein DRAP27/CD9, which up-regulates functional receptors and diphtheria toxin ..." in: The EMBO journal, Vol. 13, Issue 10, pp. 2322-30, (1994) (PubMed).
: "A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF." in: Science (New York, N.Y.), Vol. 251, Issue 4996, pp. 936-9, (1991) (PubMed).
Aliases for HBEGF 抗体
heparin-binding EGF-like growth factor b (hbegfb) 抗体heparin binding EGF like growth factor (HBEGF) 抗体
Heparin-binding EGF-like growth factor (hbegf) 抗体
heparin-binding EGF-like growth factor a (hbegfa) 抗体
heparin-binding EGF-like growth factor (Hbegf) 抗体
AW047313 抗体
DTR 抗体
Dtr 抗体
DTS 抗体
Dts 抗体
DTSF 抗体
GFHB 抗体
Hb-egf 抗体
HB-EGF 抗体
hbegf 抗体
HBEGF 抗体
HEGFL 抗体
Hegfl 抗体
zgc:165443 抗体
zgc:175091 抗体
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