Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
Kuschal, Botta, Orioli, Digiovanna, Seneca, Keymolen, Tamura, Heller, Khan, Caligiuri, Lanzafame, Nardo, Ricotti, Peverali, Stephens, Zhao, Lehmann, Baranello, Levens, Kraemer, Stefanini: "GTF2E2 Mutations Destabilize the General Transcription Factor Complex TFIIE in Individuals with DNA Repair-Proficient Trichothiodystrophy." in: American journal of human genetics, Vol. 98, Issue 4, pp. 627-42, (2016) (PubMed).
Aliases for GTF2E2 抗体
general transcription factor II E, polypeptide 2 (beta subunit) (Gtf2e2) 抗体 general transcription factor IIE subunit 2 L homeolog (gtf2e2.L) 抗体 general transcription factor IIE subunit 2 (Gtf2e2) 抗体 general transcription factor IIE, polypeptide 2, beta (gtf2e2) 抗体 general transcription factor IIE subunit 2 (GTF2E2) 抗体 34kDa 抗体 AI462509 抗体 C330006J08Rik 抗体 FE 抗体 TF2E2 抗体 TFIIE-B 抗体 wu:fa05d01 抗体 zgc:77074 抗体