GTF2A1L 抗体
(General Transcription Factor IIA, 1-Like (GTF2A1L))
The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Alternative splicing for this locus has been observed and two variants, encoding distinct isoforms, have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Jul 2008].
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Latest Publications for our GTF2A1L 抗体
: "Phosphatidylinositol 3-kinase/Akt signaling is neither required for hypoxic stabilization of HIF-1 alpha nor sufficient for HIF-1-dependent target gene transcription." in: The Journal of biological chemistry, Vol. 277, Issue 17, pp. 15162-70, (2002) (PubMed).: "Constitutive activation of hypoxia-inducible genes related to overexpression of hypoxia-inducible factor-1alpha in clear cell renal carcinomas." in: Cancer research, Vol. 61, Issue 13, pp. 5215-22, (2001) (PubMed).
Aliases for GTF2A1L 抗体
general transcription factor IIA subunit 1 like (GTF2A1L) 抗体general transcription factor IIA, 1-like (Gtf2a1l) 抗体
general transcription factor 2A subunit 1 like (Gtf2a1l) 抗体
1700011N16Rik 抗体
ALF 抗体
Alf 抗体
Gtf2a1lf 抗体
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