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GSG2 产品

(Germ Cell Associated 2 (Haspin) (GSG2))

Categories

Serine/threonine-protein kinase that phosphorylates histone H3 at 'Ser-3' (H3T3ph) during mitosis. This positions and activates AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle (By similarity).

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Featured GSG2 Categories

GSG2 抗体

High quality antibodies with extensive validation data.

GSG2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

GSG2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GSG2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7245200
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
  • (1)
Cat. No. ABIN949715
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
  • (2)
Cat. No. ABIN1882168
Quantity 400 μL
Datasheet Datasheet

Recommended GSG2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1157226
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1157227
Quantity 96 tests
Datasheet Datasheet

Recommended GSG2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect cells (Sf21)
Validations
  • (2)
Cat. No. ABIN5570638
Quantity 5 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306035
Quantity 2 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306032
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our GSG2 Products

Wang, Wei, Du, Cao, Zhang, Liu, Liu, Chen, Ma: "H3 Thr3 phosphorylation is crucial for meiotic resumption and anaphase onset in oocyte meiosis." in: Cell cycle (Georgetown, Tex.), Vol. 15, Issue 2, pp. 213-24, (2016) (PubMed).

Dai, Sultan, Taylor, Higgins: "The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment." in: Genes & development, Vol. 19, Issue 4, pp. 472-88, (2005) (PubMed).

Tanaka, Iguchi, Nakamura, Kohroki, de Carvalho, Nishimune: "Cloning and characterization of human haspin gene encoding haploid germ cell-specific nuclear protein kinase." in: Molecular human reproduction, Vol. 7, Issue 3, pp. 211-8, (2001) (PubMed).

Higgins: "The Haspin gene: location in an intron of the integrin alphaE gene, associated transcription of an integrin alphaE-derived RNA and expression in diploid as well as haploid cells." in: Gene, Vol. 267, Issue 1, pp. 55-69, (2001) (PubMed).

Synonyms and alternative names related to GSG2

putative serine/threonine-protein kinase haspin homolog (LOC552287), histone H3 associated protein kinase (HASPIN), CG40080 gene product from transcript CG40080-RA (Haspin), uncharacterized LOC100122327 (LOC100122327), histone H3 associated protein kinase (Haspin), BcDNA:LD07633, CG40080, Dmel\\CG40080, haspin, HASPIN, Haspin, NV16901

Protein level used designations for GSG2

  • serine/threonine-protein kinase haspin-like protein
  • germ cell associated 2 (haspin)
  • haspin
  • CG40080-PA
  • Haspin-PA
  • putative serine/threonine-protein kinase haspin homolog
  • H-haspin
  • germ cell-specific gene 2 protein
  • haploid germ cell-specific nuclear protein kinase
  • serine/threonine-protein kinase haspin
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