GLI2 抗体
(GLI Family Zinc Finger 2 (GLI2))
This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B. [provided by RefSeq, Jul 2008].
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Latest Publications for our GLI2 抗体
: "Patched 1 Expression Correlates with Biochemical Relapse in High-Risk Prostate Cancer Patients." in: The American journal of pathology, Vol. 188, Issue 3, pp. 795-804, (2019) (PubMed).: "Direct repression of anoctamin 1 (ANO1) gene transcription by Gli proteins." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 5, pp. 6632-6642, (2019) (PubMed).
: "Differential effects of GLI2 and GLI3 in regulating cervical cancer malignancy in vitro and in vivo." in: Laboratory investigation; a journal of technical methods and pathology, (2018) (PubMed).
: "The hedgehog inhibitor GANT61 sensitizes prostate cancer cells to ionizing radiation both in vitro and in vivo." in: Oncotarget, Vol. 7, Issue 51, pp. 84286-84298, (2018) (PubMed).
: "Tissue microarray analysis indicates hedgehog signaling as a potential prognostic factor in intermediate-risk prostate cancer." in: BMC cancer, Vol. 17, Issue 1, pp. 634, (2018) (PubMed).
: "The Effect of Metformin and GANT61 Combinations on the Radiosensitivity of Prostate Cancer Cells." in: International journal of molecular sciences, Vol. 18, Issue 2, (2017) (PubMed).
: "Gli Transcription Factors Mediate the Oncogenic Transformation of Prostate Basal Cells Induced by a Kras-Androgen Receptor Axis." in: The Journal of biological chemistry, Vol. 291, Issue 49, pp. 25749-25760, (2016) (PubMed).
: "Impact of Sonic Hedgehog Pathway Expression on Outcome in HPV Negative Head and Neck Carcinoma Patients after Surgery and Adjuvant Radiotherapy." in: PLoS ONE, Vol. 11, Issue 12, pp. e0167665, (2016) (PubMed).
: "Autophagy is related to the hedgehog signaling pathway in human gastric adenocarcinoma: prognostic significance of Beclin-1 and Gli2 expression in human gastric adenocarcinoma." in: Pathology, research and practice, Vol. 211, Issue 4, pp. 308-15, (2015) (PubMed).
: "Intrinsic facilitation of adult peripheral nerve regeneration by the Sonic hedgehog morphogen." in: Experimental neurology, Vol. 271, pp. 493-505, (2015) (PubMed).
Aliases for GLI2 抗体
GLI family zinc finger 2 (GLI2) 抗体GLI family zinc finger 2 (Gli2) 抗体
GLI-Kruppel family member GLI2 (Gli2) 抗体
AW546128 抗体
GLI2/GLI4 抗体
GLI3 抗体
HPE9 抗体
THP1 抗体
THP2 抗体
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