FTH1 抗体
(Ferritin, Heavy Polypeptide 1 (FTH1))
This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
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Latest Publications for our FTH1 抗体
: "Phosphoproteomic identification of ULK substrates reveals VPS15-dependent ULK/VPS34 interplay in the regulation of autophagy." in: The EMBO journal, Vol. 40, Issue 14, pp. e105985, (2021) (PubMed).: "Salinomycin kills cancer stem cells by sequestering iron in lysosomes." in: Nature chemistry, Vol. 9, Issue 10, pp. 1025-1033, (2019) (PubMed).
: "Autophagy-Independent Lysosomal Targeting Regulated by ULK1/2-FIP200 and ATG9." in: Cell reports, Vol. 20, Issue 10, pp. 2341-2356, (2018) (PubMed).
: "Dedicated SNAREs and specialized TRIM cargo receptors mediate secretory autophagy." in: The EMBO journal, Vol. 36, Issue 1, pp. 42-60, (2017) (PubMed).
: "Calcium channel blockers ameliorate iron overload-associated hepatic fibrosis by altering iron transport and stellate cell apoptosis." in: Toxicology and applied pharmacology, Vol. 301, pp. 50-60, (2016) (PubMed).
: "Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis." in: eLife, Vol. 4, (2016) (PubMed).
: "Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy." in: Nature, Vol. 509, Issue 7498, pp. 105-9, (2014) (PubMed).
: "Fungal iron availability during deep seated candidiasis is defined by a complex interplay involving systemic and local events." in: PLoS pathogens, Vol. 9, Issue 10, pp. e1003676, (2013) (PubMed).
: "Genetically programmed superparamagnetic behavior of mammalian cells." in: Journal of biotechnology, Vol. 162, Issue 2-3, pp. 237-45, (2012) (PubMed).
: "Label-free biosensing with functionalized nanopipette probes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 12, pp. 4611-6, (2009) (PubMed).
Aliases for FTH1 抗体
ferritin heavy chain 1 (FTH1) 抗体ferritin, heavy polypeptide 1 L homeolog (fth1.L) 抗体
ferritin, heavy polypeptide 1 S homeolog (fth1.S) 抗体
ferritin heavy polypeptide 1 (Fth1) 抗体
ferritin heavy chain 1 (Fth1) 抗体
ferritin, heavy polypeptide 1a (fth1a) 抗体
ferritin (EAMY_RS19690) 抗体
ferritin, heavy polypeptide 1 (fth1) 抗体
tudor domain containing 9 (TDRD9) 抗体
ferritin, heavy polypeptide 1 (FTH1) 抗体
ferritin, heavy polypeptide 1 a (fth1a) 抗体
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plif 抗体
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zeh1145 抗体
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