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FNTA 产品

(Farnesyltransferase, CAAX Box, alpha (FNTA))

Categories

Prenyltransferases can attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of proteins with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq, May 2010].

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Featured FNTA Categories

FNTA 抗体

High quality antibodies with extensive validation data.

FNTA ELISA试剂盒

Reliable ELISA kits for a wide range of species.

FNTA 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended FNTA 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
  • (3)
Cat. No. ABIN7441346
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN947877
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7129533
Quantity 100 μL
Datasheet Datasheet

Recommended FNTA ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955698
Quantity 96 tests
Datasheet Datasheet
Reactivity Various Species
Analytical Method Quantitative Competition ELISA
Validations
  • (2)
Cat. No. ABIN1133744
Quantity 96 tests
Datasheet Datasheet
Reactivity Various Species
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN5594906
Quantity 96 tests
Datasheet Datasheet

Recommended FNTA 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1354288
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3080227
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3122911
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our FNTA Products

Lin, Shen, Hsu, Lin: "A High-Fructose-High-Coconut Oil Diet Induces Dysregulating Expressions of Hippocampal Leptin and Stearoyl-CoA Desaturase, and Spatial Memory Deficits in Rats." in: Nutrients, Vol. 9, Issue 6, (2018) (PubMed).

Amin, Asaad, Abdel Salam, El-Abhar, Arbid et al.: "Novel CoQ10 antidiabetic mechanisms underlie its positive effect: modulation of insulin and adiponectine receptors, Tyrosine kinase, PI3K, glucose transporters, sRAGE and visfatin in insulin ..." in: PLoS ONE, Vol. 9, Issue 2, pp. e89169, (2014) (PubMed).

Chiba, Sato, Misawa: "Upregulation of geranylgeranyltransferase I in bronchial smooth muscle of mouse experimental asthma: its inhibition by lovastatin." in: Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, Vol. 46, Issue 1, pp. 57-64, (2010) (PubMed).

Wang, Danielson, Li, Shah, Kim, Donahoe: "The p21(RAS) farnesyltransferase alpha subunit in TGF-beta and activin signaling." in: Science (New York, N.Y.), Vol. 271, Issue 5252, pp. 1120-2, (1996) (PubMed).

Zhang, Diehl, Kohl, Gibbs, Giros, Casey, Omer: "cDNA cloning and expression of rat and human protein geranylgeranyltransferase type-I." in: The Journal of biological chemistry, Vol. 269, Issue 5, pp. 3175-80, (1994) (PubMed).

Andres, Milatovich, Ozçelik, Wenzlau, Brown, Goldstein, Francke: "cDNA cloning of the two subunits of human CAAX farnesyltransferase and chromosomal mapping of FNTA and FNTB loci and related sequences." in: Genomics, Vol. 18, Issue 1, pp. 105-12, (1994) (PubMed).

Omer, Kral, Diehl, Prendergast, Powers, Allen, Gibbs, Kohl: "Characterization of recombinant human farnesyl-protein transferase: cloning, expression, farnesyl diphosphate binding, and functional homology with yeast prenyl-protein transferases." in: Biochemistry, Vol. 32, Issue 19, pp. 5167-76, (1993) (PubMed).

Synonyms and alternative names related to FNTA

farnesyltransferase A (FTA), farnesyltransferase, CAAX box, alpha (FNTA), farnesyltransferase, CAAX box, alpha (Fnta), ATFTA, FARNESYLTRANSFERASE A, farnesyltransferase A, FARNESYLTRANSFERASE SUBUNIT A, FPTA, FTA, PFAS, PFT/PGGT-IALPHA, PGGT1A, PLP, PLURIPETALA, PTAR2

Protein level used designations for FNTA

  • FTase-alpha
  • GGTase-I-alpha
  • farnesyl-protein transferase alpha-subunit
  • protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
  • protein prenyltransferase alpha subunit repeat containing 2
  • ras proteins prenyltransferase subunit alpha
  • type I protein geranyl-geranyltransferase alpha subunit
  • CAAX farnesyltransferase subunit alpha
  • type I protein geranyl-geranyltransferase subunit alpha
  • Farnesyltransferase, subunit alpha
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