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FMO5 蛋白

(Flavin Containing Monooxygenase 5 (FMO5))
Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009].

Popular FMO5 蛋白

Aliases for FMO5 蛋白

flavin containing monooxygenase 5 S homeolog (fmo5.S) 蛋白
flavin containing monooxygenase 5 (fmo5) 蛋白
flavin containing monooxygenase 5 (MCYG_00559) 蛋白
flavin containing monooxygenase 5 (FMO5) 蛋白
flavin containing monooxygenase 5 (Fmo5) 蛋白
5033418D19Rik 蛋白
AI195026 蛋白
MGC68633 蛋白
MGC108355 蛋白
sb:cb1007 蛋白
wu:fc05b01 蛋白
wu:fk47g04 蛋白
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