FKBP5 抗体
(FK506 Binding Protein 5 (FKBP5))
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009].
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Rockland Original
Latest Publications for our FKBP5 抗体
: "Endothelial glucocorticoid receptor promoter methylation according to dexamethasone sensitivity." in: Journal of molecular endocrinology, (2015) (PubMed).: "FKBP51 employs both scaffold and isomerase functions to promote NF-?B activation in melanoma." in: Nucleic acids research, Vol. 43, Issue 14, pp. 6983-93, (2015) (PubMed).
: "Immunomodulatory pathways regulate expression of a spliced FKBP51 isoform in lymphocytes of melanoma patients." in: Pigment cell & melanoma research, Vol. 28, Issue 4, pp. 442-52, (2015) (PubMed).
: "FKBP51 increases the tumour-promoter potential of TGF-beta." in: Clinical and translational medicine, Vol. 3, Issue 1, pp. 1, (2014) (PubMed).
: "FK506 binding protein 51 positively regulates melanoma stemness and metastatic potential." in: Cell death & disease, Vol. 4, pp. e578, (2013) (PubMed).
: "Org 214007-0: a novel non-steroidal selective glucocorticoid receptor modulator with full anti-inflammatory properties and improved therapeutic index. ..." in: PLoS ONE, Vol. 7, Issue 11, pp. e48385, (2012) (PubMed).
Aliases for FKBP5 抗体
FK506 binding protein 5 (FKBP5) 抗体FK506 binding protein 5 (fkbp5) 抗体
FK506 binding protein 5 (Fkbp5) 抗体
AIG6 抗体
D17Ertd592e 抗体
Dit1 抗体
FKBP-5 抗体
FKBP5 抗体
FKBP51 抗体
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P54 抗体
PPIase 抗体
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si:zc263a23.8 抗体
wu:fc31g11 抗体
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zgc:64082 抗体
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