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Fibroblast Growth Factor Receptor 产品

(Fibroblast Growth Factor Receptor (FGFR))
Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and normal skeletogenesis. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol- 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Promotes phosphorylation of SHC1, STAT1 and PTPN11/SHP2. In the nucleus, enhances RPS6KA1 and CREB1 activity and contributes to the regulation of transcription. FGFR1 signaling is down-regulated by ubiquitination, internalization and degradation (By similarity).

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Featured Fibroblast Growth Factor Receptor Categories

Fibroblast Growth Factor Receptor 抗体

High quality antibodies with extensive validation data.

Fibroblast Growth Factor Receptor ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Recommended Fibroblast Growth Factor Receptor 抗体

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Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN2267319
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN2267321
Quantity 1 mg
Datasheet Datasheet

Recommended Fibroblast Growth Factor Receptor ELISA试剂盒

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Validations
Cat. No.
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Reactivity Pig
Analytical Method Quantitative Competition ELISA
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Cat. No. ABIN778747
Quantity 96 tests
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Reactivity Goat
Analytical Method Quantitative Competition ELISA
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Cat. No. ABIN989383
Quantity 96 tests
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Reactivity Cow
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN989385
Quantity 96 tests
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Recommended Fibroblast Growth Factor Receptor 蛋白

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Source
Validations
Cat. No.
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Datasheet
Reactivity Sea Squirt
Source Yeast
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Cat. No. ABIN1628579
Quantity 1 mg
Datasheet Datasheet
Reactivity Hydra
Source Yeast
Validations
Cat. No. ABIN1623910
Quantity 1 mg
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Synonyms and alternative names related to Fibroblast Growth Factor Receptor

heartless (htl), fibroblast growth factor receptor 1 L homeolog (fgfr1.L), fibroblast growth factor receptor (FGFR), fibroblast growth factor receptor 1 S homeolog (fgfr1.S), fibroblast growth factor receptor (fgfr), fibroblast growth factor receptor 1 (FGFR1), fibroblast growth factor receptor 1 (fgfr1), fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) L homeolog (fgfr3.L), basic fibroblast growth factor receptor 1 (CpipJ_CPIJ005849), ach, bfgfr, cd331, cd333, cek, cek2, CG7223, CT22273, CT39172, DFGF-R1, DFGF-R2, DFR-1, Dfr-1, DFR1, Dfr1, DFR1/DFGF-R2, Dmel\\CG7223, DmHD-38, DPR3, Dtk1, dtk1, DTRK(FR1), EMS2, FGF-R2, fgfbr, FGFR, fgfr, fgfr-1, fgfr-3, fgfr1, FGFR2, flg, FLG-1, flt-2, flt2, FR1, Fr1, hbgfr, HD-38, hsfgfr3ex, Htl, HTL/FGFR1, i79, i100, i150, j372, jtk4, kal2, n-sam, ogd, Tk1, x1fgfr, X1FGFR, XFGFR-1, xfgfr1, XFGFRA2

Protein level used designations for Fibroblast Growth Factor Receptor

  • CG7223-PA
  • CG7223-PB
  • CG7223-PC
  • FGF receptor
  • fibroblast growth factor receptor
  • fibroblast growth factor receptor 1
  • htl-PA
  • htl-PB
  • htl-PC
  • FGFR-1
  • fibroblast growth factor receptor-1
  • fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)
  • ibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)
  • basic fibroblast growth factor receptor 1
  • basic fibroblast growth factor receptor 1-like
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