FDPS 抗体
(Farnesyl Diphosphate Synthase (FDPS))
This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2008].
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57 results
FDPS
适用: 人
ELISA, FACS
宿主: 兔
Monoclonal
12H412H4
unconjugated
Recombinant Antibody
FDPS
适用: 人, 大鼠, 小鼠, 犬, 马, Pig, 兔, Cow, 豚鼠
WB, IHC
宿主: 兔
Polyclonal
unconjugated
1 image
Latest Publications for our FDPS 抗体
: "Liposome encapsulated zoledronate favours M1-like behaviour in murine macrophages cultured with soluble factors from breast cancer cells." in: BMC cancer, Vol. 15, pp. 4, (2015) (PubMed).: "Altered expression of farnesyl pyrophosphate synthase in prostate cancer: evidence for a role of the mevalonate pathway in disease progression?" in: World journal of urology, Vol. 31, Issue 2, pp. 345-50, (2013) (PubMed).
: "5-Aza-2'-deoxycytidine induced growth inhibition of leukemia cells through modulating endogenous cholesterol biosynthesis." in: Molecular & cellular proteomics : MCP, Vol. 11, Issue 7, pp. M111.016915, (2012) (PubMed).
: "Sterol-regulatory-element-binding protein 2 and nuclear factor Y control human farnesyl diphosphate synthase expression and affect cell proliferation in hepatoblastoma cells." in: The Biochemical journal, Vol. 429, Issue 2, pp. 347-57, (2010) (PubMed).
: "Mevalonate pathway intermediates downregulate zoledronic acid-induced isopentenyl pyrophosphate and ATP analog formation in human breast cancer cells." in: Biochemical pharmacology, Vol. 79, Issue 5, pp. 777-83, (2010) (PubMed).
: "Reduced expression of the mevalonate pathway enzyme farnesyl pyrophosphate synthase unveils recognition of tumor cells by Vgamma9Vdelta2 T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 12, pp. 8118-24, (2009) (PubMed).
: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).
: "Isolation and sequence of the human farnesyl pyrophosphate synthetase cDNA. Coordinate regulation of the mRNAs for farnesyl pyrophosphate synthetase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, ..." in: The Journal of biological chemistry, Vol. 265, Issue 8, pp. 4607-14, (1990) (PubMed).
: "Cloning, analysis, and bacterial expression of human farnesyl pyrophosphate synthetase and its regulation in Hep G2 cells." in: Biochemistry, Vol. 28, Issue 20, pp. 8129-35, (1990) (PubMed).
Aliases for FDPS 抗体
Farnesyl pyrophosphate synthase (Fpps) 抗体farnesyl diphosphate synthase (fdps) 抗体
farnesyl diphosphate synthase L homeolog (fdps.L) 抗体
farnesyl pyrophosphate synthase (MGG_08649) 抗体
farnesyl pyrophosphate synthetase (TP03_0857) 抗体
farnesyl pyrophosphate synthetase (Tb09.160.4300) 抗体
farnesyl-pyrophosphate synthetase (fpp) 抗体
farnesyl pyrophosphate synthetase (BBOV_I000120) 抗体
FDP synthase (fps) 抗体
Farnesyl pyrophosphate synthetase (fpps) 抗体
farnesyl diphosphate synthase (FDPS) 抗体
farnesyl diphosphate synthase (Fdps) 抗体
farnesyl diphosphate synthetase (Fdps) 抗体
farnesyl pyrophosphate synthase 1 (fps1) 抗体
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