FAM84A 蛋白
(Family with Sequence Similarity 84, Member A (FAM84A))
Component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT- associated PML bodies (APBs). Has in vitro ubiquitin ligase activity in presence of NDNL2. Is involved in positive regulation of response to DNA damage stimulus.
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| FAM84A Protein (AA 1-292) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| FAM84A Protein (AA 1-292) (GST tag) | 人 | 小麦胚 |
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| FAM84A 蛋白 | 人 | 大肠杆菌（E. Coli） |
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| FAM84A Protein (Myc-DYKDDDDK Tag) | 人 | HEK-293 Cells |
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| FAM84A Protein (AA 1-297) (His tag) | Cow | 酵母菌 |
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Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- WB (Western Blotting: 有验证图片)
- AbP (Antibody Production: 所列应用)
- STD (Standard: 所列应用)
1 reference - 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Protein
- ELISA (ELISA: 所列应用)
- 宿主
- Cow
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Latest Publications for our FAM84A 蛋白
: "Distinct oligoclonal band antibodies in multiple sclerosis recognize ubiquitous self-proteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 28, pp. 7864-9, (2016) (PubMed).
Aliases for FAM84A 蛋白
family with sequence similarity 84, member A (Fam84a) 蛋白family with sequence similarity 84 member A (FAM84A) 蛋白
family with sequence similarity 84, member A (fam84a) 蛋白
family with sequence similarity 84 member A (Fam84a) 蛋白
2310003N02Rik 蛋白
4731402F03Rik 蛋白
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PP11517 蛋白
RGD1305779 蛋白
zgc:63724 蛋白
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