FAM208A 产品
(Family with Sequence Similarity 208, Member A (FAM208A))
Categories
Component of the HUSH complex, a multiprotein complex that mediates epigenetic repression. The HUSH complex is recruited to genomic loci rich in H3K9me3 and is probably required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3. {ECO:0000250|UniProtKB:Q9UK61}.
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Recommended FAM208A 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC (p), IF
Validations
- (2)
Cat. No.
ABIN5573378
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC (p)
Validations
- (1)
Cat. No.
ABIN5573377
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN6140453
Quantity
100 μL
Datasheet
Datasheet
Recommended FAM208A 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3135659
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our FAM208A Products
: "GENE SILENCING. Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells." in: Science (New York, N.Y.), Vol. 348, Issue 6242, pp. 1481-5, (2015) (PubMed).: "The first mouse mutants of D14Abb1e (Fam208a) show that it is critical for early development." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 25, Issue 7-8, pp. 293-303, (2014) (PubMed).
Synonyms and alternative names related to FAM208A
family with sequence similarity 208 member A L homeolog (fam208a.L), family with sequence similarity 208 member A (FAM208A), C3orf63, c3orf63-a, c3orf63.1, fam208a, rap140, RAP140, se89-1Protein level used designations for FAM208A
- protein FAM208A
- retinoblastoma-associated protein 140
- uncharacterized protein C3orf63 homolog
- CTCL tumor antigen se89-1
- retinoblastoma-associated protein RAP140
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