Fc receptors specifically bind to the Fc region of immunoglobulins (Igs) to mediate the unique functions of each Ig class. FAIM3 encodes an Fc receptor for IgM (see MIM 147020) (Kubagawa et al., 2009 [PubMed 19858324]\; Shima et al., 2010 [PubMed 20042454]).[supplied by OMIM, Jul 2010].
Murakami, Narayanan, Su, Childs, Krzewski, Borrego, Weck, Coligan: "Toso, a functional IgM receptor, is regulated by IL-2 in T and NK cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 189, Issue 2, pp. 587-97, (2012) (PubMed).
Li, Kubagawa, McCollum, Wilson, Motohashi, Bertoli, Barton, Barnes, Davis, Kubagawa: "Enhanced levels of both the membrane-bound and soluble forms of IgM Fc receptor (Fc?R) in patients with chronic lymphocytic leukemia." in: Blood, Vol. 118, Issue 18, pp. 4902-9, (2011) (PubMed).
Proto-Siqueira, Panepucci, Careta, Lee, Clear, Morris, Owen, Rizzatti, Silva, Falcão, Zago, Gribben: "SAGE analysis demonstrates increased expression of TOSO contributing to Fas-mediated resistance in CLL." in: Blood, Vol. 112, Issue 2, pp. 394-7, (2008) (PubMed).
Song, Jacob: "The mouse cell surface protein TOSO regulates Fas/Fas ligand-induced apoptosis through its binding to Fas-associated death domain." in: The Journal of biological chemistry, Vol. 280, Issue 10, pp. 9618-26, (2005) (PubMed).
Curtin, Cotter: "Live and let die: regulatory mechanisms in Fas-mediated apoptosis." in: Cellular signalling, Vol. 15, Issue 11, pp. 983-92, (2003) (PubMed).
Aliases for FAIM3 抗体
Fc fragment of IgM receptor (FCMR) 抗体 Fc fragment of IgM receptor (Fcmr) 抗体 1810037B05Rik 抗体 FAIM3 抗体 FCMR 抗体 FcmuR 抗体 TOSO 抗体 Toso 抗体