FADD 抗体
(Fas (TNFRSF6)-Associated Via Death Domain (FADD))
The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008].
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112 results :
FADD
适用: 人
WB, IP
宿主: 兔
Polyclonal
unconjugated
1 reference
FADD
适用: 人
ELISA, FACS
宿主: 小鼠
Monoclonal
5A6A2
unconjugated
FADD
适用: 人, 小鼠, 大鼠, 猴, Pig
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
1 image
1 reference
FADD
适用: 人, 小鼠, 大鼠
WB, IHC, ELISA, IF, ICC
宿主: 兔
Polyclonal
unconjugated
Latest Publications for our FADD 抗体
: "Diabetes induces IL-17A-Act1-FADD-dependent retinal endothelial cell death and capillary degeneration." in: Journal of diabetes and its complications, Vol. 33, Issue 9, pp. 668-674, (2019) (PubMed).: "Edaravone attenuates neuronal apoptosis in hypoxic-ischemic brain damage rat model via suppression of TRAIL signaling pathway." in: The international journal of biochemistry & cell biology, Vol. 99, pp. 169-177, (2018) (PubMed).
: "15, 16-Dihydrotanshinone I Inhibits Hemangiomas through Inducing Pro-apoptotic and Anti-angiogenic Mechanisms in Vitro and in Vivo." in: Frontiers in pharmacology, Vol. 9, pp. 25, (2018) (PubMed).
: "D4F alleviates macrophage-derived foam cell apoptosis by inhibiting the NF-κB-dependent Fas/FasL pathway." in: Scientific reports, Vol. 7, Issue 1, pp. 7333, (2017) (PubMed).
: "Early septic insult in neonatal pigs increases serum and urinary soluble Fas ligand and decreases kidney function without inducing significant renal apoptosis." in: Renal failure, pp. 1-12, (2016) (PubMed).
: "FADD-calmodulin interaction: a novel player in cell cycle regulation." in: Biochimica et biophysica acta, Vol. 1803, Issue 8, pp. 898-911, (2010) (PubMed).
: "Akt-phosphorylated mitogen-activated kinase-activating death domain protein (MADD) inhibits TRAIL-induced apoptosis by blocking Fas-associated death domain (FADD) association with death receptor 4." in: The Journal of biological chemistry, Vol. 285, Issue 29, pp. 22713-22, (2010) (PubMed).
: "Lack of Fas-pathway gene mutations in primary resected esophageal squamous cell carcinoma." in: Chang Gung medical journal, Vol. 33, Issue 2, pp. 145-51, (2010) (PubMed).
: "Hydroxylase inhibition abrogates TNF-alpha-induced intestinal epithelial damage by hypoxia-inducible factor-1-dependent repression of FADD." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 10, pp. 6306-16, (2010) (PubMed).
: "Dengue hemorrhagic fever is associated with polymorphisms in JAK1." in: European journal of human genetics : EJHG, Vol. 18, Issue 11, pp. 1221-7, (2010) (PubMed).
Aliases for FADD 抗体
Fas associated via death domain (FADD) 抗体Fas (TNFRSF6)-associated via death domain (Fadd) 抗体
Fas associated via death domain (Fadd) 抗体
Fas associated via death domain S homeolog (fadd.S) 抗体
Fas (tnfrsf6)-associated via death domain (fadd) 抗体
adaptor 抗体
fadd 抗体
MORT1 抗体
Mort1 抗体
mort1 抗体
Mort1/FADD 抗体
TNFRSF6 抗体
xfadd 抗体
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