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ERVW-1 蛋白

(Endogenous Retrovirus Group W, Member 1 (ERVW-1))
Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on chromosome 7 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010].

1 results :

ERVW-1 宿主: 人 宿主: 小麦胚 Recombinant AA, AP, ELISA, WB
Pubmed 1 reference
产品编号 ABIN1353105
 
  • 类型 Protein
    • Protein
  • 应用范围
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • ELISA
    • Western Blotting (WB)
  • 适用
    • Human
  • 论文引用
  • 图像
  • 抗体来源
    • Wheat germ
  • 抗原表位
    • AA 116-215
  • 标记
    • GST tag
  • 蛋白类型
    • Recombinant
  • Supplier
    • antibodies-online

Latest Publications for our ERVW-1 蛋白

Holder, Tower, Forbes, Mulla, Aplin, Abrahams: "Immune cell activation by trophoblast-derived microvesicles is mediated by syncytin 1." in: Immunology, Vol. 136, Issue 2, pp. 184-91, (2012) (PubMed).

Aliases for ERVW-1 蛋白

endogenous retrovirus group W member 1, envelope (ERVW-1) 蛋白
ENV 蛋白
ENVW 蛋白
ERVWE1 蛋白
HERV-7q 蛋白
HERV-W-ENV 蛋白
HERV7Q 蛋白
HERVW 蛋白
HERVWENV 蛋白
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