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ERO1LB 蛋白

(ERO1-Like beta (ERO1LB))
Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. Acts by oxidizing directly P4HB/PDI isomerase through a direct disulfide exchange. Does not act as a direct oxidant of folding substrate, but relies on P4HB/PDI to transfer oxidizing equivalent. Associates with ERP44 but not with GRP54, demonstrating that it does not oxidize all PDI related proteins and can discriminate between PDI and related proteins. Its reoxidation probably involves electron transfer to molecular oxygen via FAD. Acts independently of glutathione. May be responsible for a significant proportion of reactive oxygen species (ROS) in the being a source of oxidative stress. Required for the folding of cell, thereby being a source of oxidative stress.

2 results :

ERO1LB 宿主: 人 宿主: 小麦胚 Recombinant AA, AP, ELISA, WB
产品编号 ABIN1353090
 
ERO1LB 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2720504
 
  • 类型 Protein
    • Protein
  • 应用范围
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • ELISA
    • Standard (STD)
    • Western Blotting (WB)
  • 适用
    • Human
  • 图像
  • Carrier free only
  • 抗体来源
    • HEK-293 Cells
    • Wheat germ
  • 抗原表位
    • AA 1-467
  • 标记
    • GST tag
    • Myc-DYKDDDDK Tag
  • 蛋白类型
    • Recombinant
  • Supplier
    • OriGene
    • antibodies-online

Aliases for ERO1LB 蛋白

endoplasmic reticulum oxidoreductase 1 beta (Ero1b) 蛋白
endoplasmic reticulum oxidoreductase 1 beta (ERO1B) 蛋白
ERO1-like beta (S. cerevisiae) (Ero1lb) 蛋白
1300013B24Rik 蛋白
1700065B09Rik 蛋白
AI447560 蛋白
ero1-beta 蛋白
RGD1563548 蛋白
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