This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].
endothelin receptor type A (EDNRA) 蛋白 endothelin receptor type A (Ednra) 蛋白 endothelin receptor type Aa (ednraa) 蛋白 endothelin receptor type A L homeolog (ednra.L) 蛋白 endothelin receptor type A (ednra) 蛋白 endothelin receptor type Ab (ednrab) 蛋白 ednr-a 蛋白 ednra 蛋白 ednraa 蛋白 Endor 蛋白 ET-A 蛋白 ET-AR 蛋白 ETA 蛋白 Eta 蛋白 ETa 蛋白 eta 蛋白 ETA-R 蛋白 ETAR 蛋白 etar 蛋白 ETRA 蛋白 etra 蛋白 Gpcr10 蛋白 hET-AR 蛋白 RGD1559432 蛋白 wu:fb75g12 蛋白 zgc:85942 蛋白