EIF3A 抗体
(Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A))
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
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Latest Publications for our EIF3A 抗体
: "A threonyl-tRNA synthetase-mediated translation initiation machinery." in: Nature communications, Vol. 10, Issue 1, pp. 1357, (2019) (PubMed).: "Picornavirus 2A protease regulates stress granule formation to facilitate viral translation." in: PLoS pathogens, Vol. 14, Issue 2, pp. e1006901, (2018) (PubMed).
: "ABCE1 is essential for S phase progression in human cells." in: Cell cycle (Georgetown, Tex.), Vol. 15, Issue 9, pp. 1234-47, (2016) (PubMed).
: "eIF3 targets cell-proliferation messenger RNAs for translational activation or repression." in: Nature, Vol. 522, Issue 7554, pp. 111-4, (2015) (PubMed).
: "EJC core component MLN51 interacts with eIF3 and activates translation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 15, pp. 5903-8, (2013) (PubMed).
: "Interferon-dependent engagement of eukaryotic initiation factor 4B via S6 kinase (S6K)- and ribosomal protein S6K-mediated signals." in: Molecular and cellular biology, Vol. 29, Issue 10, pp. 2865-75, (2009) (PubMed).
Aliases for EIF3A 抗体
eukaryotic translation initiation factor 3 subunit A (EIF3A) 抗体eukaryotic translation initiation factor 3, subunit A (Eif3a) 抗体
eukaryotic translation initiation factor 3 subunit A S homeolog (eif3a.S) 抗体
translation initiation factor eIF3a (tif32) 抗体
eukaryotic translation initiation factor 3 subunit A (Eif3a) 抗体
A830012B05Rik 抗体
Csma 抗体
EIF3 抗体
Eif3 抗体
eIF3 p110 抗体
eIF3-p170 抗体
eIF3-theta 抗体
eIF3a 抗体
EIF3S10 抗体
Eif3s10 抗体
eif3s10 抗体
EIF6 抗体
mKIAA0139 抗体
P167 抗体
p180 抗体
p185 抗体
TIF32 抗体
ZH12 抗体
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