51 Calcium Modulating Ligand (CAMLG) 抗体 from 11 manufacturers are available on www.antibodies-online.cn.
Calcium Modulating Ligand (CAMLG) 抗原简介
The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.
Alternative names and synonyms associated with Calcium Modulating Ligand (CAMLG)