CAMLG 抗体
(Calcium Modulating Ligand (CAMLG))
The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq, Jul 2008].
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Aliases for CAMLG 抗体
calcium modulating ligand L homeolog (camlg.L) 抗体calcium modulating ligand (CAMLG) 抗体
calcium modulating ligand (camlg) 抗体
calcium modulating ligand (Caml) 抗体
calcium modulating ligand (Camlg) 抗体
AI385748 抗体
CAML 抗体
Caml 抗体
Camlg 抗体
MGC53900 抗体
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