This gene encodes a transcriptional regulator that belongs to the EGR family of C2H2-type zinc-finger proteins. It is an immediate-early growth response gene which is induced by mitogenic stimulation. The protein encoded by this gene participates in the transcriptional regulation of genes in controling biological rhythm. It may also play a role in a wide variety of processes including muscle development, lymphocyte development, endothelial cell growth and migration, and neuronal development. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2010].
Pio, Jia, Baron, Mercola: "Early growth response 3 (Egr3) is highly over-expressed in non-relapsing prostate cancer but not in relapsing prostate cancer." in: PLoS ONE, Vol. 8, Issue 1, pp. e54096, (2013) (PubMed).
Hinze, Mayer, Harst, von Kügelgen: "Adenosine A(3) receptor-induced proliferation of primary human coronary smooth muscle cells involving the induction of early growth response genes." in: Journal of molecular and cellular cardiology, Vol. 53, Issue 5, pp. 639-45, (2012) (PubMed).
Aliases for EGR3 抗体
early growth response 3 (EGR3) 抗体 early growth response 3 (Egr3) 抗体 early growth response 3 (egr3) 抗体 early growth response protein 3 (EGR-3) 抗体 EGR-3 抗体 PILOT 抗体 Pilot 抗体 zgc:92020 抗体