Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It lacks mannosidase activity.
custom-made
EDEM1
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
EDEM1
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
ER degradation enhancer, mannosidase alpha-like 1 (edem1) 蛋白 ER degradation enhancing alpha-mannosidase like protein 1 (edem1) 蛋白 ER degradation enhancing alpha-mannosidase like protein 1 (EDEM1) 蛋白 ER degradation-enhancing alpha-mannosidase-like protein 1 (LOC100637820) 蛋白 ER degradation enhancing alpha-mannosidase like protein 1 L homeolog (edem1.L) 蛋白 ER degradation enhancer, mannosidase alpha-like 1 (Edem1) 蛋白 ER degradation enhancing alpha-mannosidase like protein 1 (Edem1) 蛋白 A130059K23Rik 蛋白 edem 蛋白 EDEM 蛋白 EDEM1 蛋白 mKIAA0212 蛋白 RGD1563633 蛋白 zgc:55816 蛋白