E3 SUMO-Protein Ligase NSE2 蛋白
(E3 SUMO-Protein Ligase NSE2 (NSMCE2))
E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. Is not be required for the stability of the complex.The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. Acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, the shelterin complex subunits TERF1, TERF2, TINF2 and TERF2IP, and maybe the cohesin components RAD21 and STAG2. Required for recruitment of telomeres to PML nuclear bodies. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair. Required for sister chromatid cohesion during prometaphase and mitotic progression (By similarity).
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| NSMCE2 Protein (AA 1-247) (His tag) | 人 | HEK-293 Cells |
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| NSMCE2 Protein (AA 1-247) (His tag) | 小鼠 | HEK-293 Cells |
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| NSMCE2 Protein (AA 1-247) (GST tag) | 人 | 小麦胚 |
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| NSMCE2 Protein (AA 1-310) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| NSMCE2 蛋白 | 人 | 大肠杆菌（E. Coli） |
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| NSMCE2 Protein (AA 1-247) (Strep Tag) | 人 | Cell-free protein synthesis (CFPS) |
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| NSMCE2 Protein (AA 1-247) (Strep Tag) | 小鼠 | Cell-free protein synthesis (CFPS) |
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| NSMCE2 Protein (AA 11-309) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| NSMCE2 Protein (Myc-DYKDDDDK Tag) | 人 | HEK-293 Cells |
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| NSMCE2 Protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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| NSMCE2 Protein (AA 1-250) (His tag) | Schizosaccharomyces pombe | 酵母菌 |
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| NSMCE2 Protein (AA 1-238) (His tag) | 非洲爪蟾 | 酵母菌 |
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| NSMCE2 Protein (AA 1-248) (His tag) | Cow | 酵母菌 |
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| NSMCE2 Protein (AA 1-247) (His tag) | 大鼠 | 酵母菌 |
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Protein
- PS (Protein Structure: 有验证图片)
- 质量等级
- custom-made
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Protein
- PS (Protein Structure: 有验证图片)
- 质量等级
- custom-made
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 85 %
Protein
- ELISA (ELISA: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- 质量等级
- custom-made
- 宿主
- 人
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- ELISA (ELISA: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- 质量等级
- custom-made
- 宿主
- 小鼠
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- WB (Western Blotting: 有验证图片)
- AbP (Antibody Production: 所列应用)
- STD (Standard: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Protein
- WB (Western Blotting: 有验证图片)
- AbP (Antibody Production: 所列应用)
- STD (Standard: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Protein
- ELISA (ELISA: 所列应用)
- 宿主
- Schizosaccharomyces pombe
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- ELISA (ELISA: 所列应用)
- 宿主
- 非洲爪蟾
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- ELISA (ELISA: 所列应用)
- 宿主
- Cow
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- ELISA (ELISA: 所列应用)
- 宿主
- 大鼠
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Aliases for E3 SUMO-Protein Ligase NSE2 蛋白
family with sequence similarity 84 member B (FAM84B) 蛋白NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase (Nsmce2) 蛋白
NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase (NSMCE2) 蛋白
NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase L homeolog (nsmce2.L) 蛋白
Smc5-6 complex non-SMC subunit 2 (nse2) 蛋白
family with sequence similarity 84, member B (Fam84b) 蛋白
family with sequence similarity 84, member B (fam84b) 蛋白
1110014D18Rik 蛋白
AI661537 蛋白
BCMP101 蛋白
BF642811 蛋白
C8orf36 蛋白
D330050I23Rik 蛋白
MMS21 蛋白
Non-SMC element 2 蛋白
NSE2 蛋白
RGD1305156 蛋白
si:dkey-5e12.3 蛋白
zgc:153371 蛋白
ZMIZ7 蛋白
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