E2F2 产品
(E2F Transcription Factor 2 (E2F2))
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The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits overall 46% amino acid identity to E2F1. [provided by RefSeq, Jul 2008].
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Featured E2F2 Categories
E2F2 抗体
High quality antibodies with extensive validation data.
E2F2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
E2F2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended E2F2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (4)
Cat. No.
ABIN7172517
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, PLA
Validations
- (3)
Cat. No.
ABIN515125
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, ICC, IF
Validations
- (2)
Cat. No.
ABIN6257150
Quantity
100 μL
Datasheet
Datasheet
Recommended E2F2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955490
Quantity
96 tests
Datasheet
Datasheet
Recommended E2F2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1352231
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1352233
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3079083
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our E2F2 Products
: "GCN5 Potentiates Glioma Proliferation and Invasion via STAT3 and AKT Signaling Pathways." in: International journal of molecular sciences, Vol. 16, Issue 9, pp. 21897-910, (2016) (PubMed).: "RAE-1 ligands for the NKG2D receptor are regulated by E2F transcription factors, which control cell cycle entry." in: The Journal of experimental medicine, Vol. 209, Issue 13, pp. 2409-22, (2012) (PubMed).
: "Alpha-synuclein degradation by serine protease neurosin: implication for pathogenesis of synucleinopathies." in: Human molecular genetics, Vol. 12, Issue 20, pp. 2625-35, (2003) (PubMed).
: "E2F-6, a member of the E2F family that can behave as a transcriptional repressor." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 6, pp. 2850-5, (1998) (PubMed).
: "Nuclear localization of DP and E2F transcription factors by heterodimeric partners and retinoblastoma protein family members." in: Journal of cell science, Vol. 109 ( Pt 7), Issue 25, pp. 1717-26, (1997) (PubMed).
: "E2F transcription factor action, regulation and possible role in human cancer." in: Cell proliferation, Vol. 30, Issue 3-4, pp. 97-105, (1997) (PubMed).
: "Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4A-mediated growth suppression." in: Molecular and cellular biology, Vol. 16, Issue 3, pp. 1047-57, (1996) (PubMed).
: "E2F: a link between the Rb tumor suppressor protein and viral oncoproteins." in: Science (New York, N.Y.), Vol. 258, Issue 5081, pp. 424-9, (1992) (PubMed).
Synonyms and alternative names related to E2F2
E2F transcription factor 2 (E2F2), E2F transcription factor 2 (E2f2), si:ch211-160f23.5 (si:ch211-160f23.5), 9230110J10, CG1071, dE2F-2, dE2F2, dE2f2, de2f2, Dmel\\CG1071, E2F, E2F-2, E2F2, e2f2, E130207A07, fb40b03, wu:fb40b03Protein level used designations for E2F2
- transcription factor E2F2
- CG1071-PA
- E2f2-PA
- E2F-2
- LOW QUALITY PROTEIN: transcription factor E2F2
- E2F transcription factor 2
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