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DMAP1 产品

(DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

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This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008].

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Featured DMAP1 Categories

DMAP1 抗体

High quality antibodies with extensive validation data.

DMAP1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

DMAP1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DMAP1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (5)
Cat. No. ABIN6139677
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (1)
  • (3)
Cat. No. ABIN565960
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7150197
Quantity 100 μg
Datasheet Datasheet

Recommended DMAP1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1130039
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1130040
Quantity 96 tests
Datasheet Datasheet

Recommended DMAP1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1351708
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3092188
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3137265
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our DMAP1 Products

Wang, Liang, Li, Tsoi, Zhang, Wang, Go, Chiu, Ng, Sung, Yu: "MDGA2 is a novel tumour suppressor cooperating with DMAP1 in gastric cancer and is associated with disease outcome." in: Gut, (2015) (PubMed).

Yamaguchi, Takenobu, Ohira, Nakazawa, Yoshida, Akita, Shimozato, Iwama, Nakagawara, Kamijo: "Novel 1p tumour suppressor Dnmt1-associated protein 1 regulates MYCN/ataxia telangiectasia mutated/p53 pathway." in: European journal of cancer (Oxford, England : 1990), Vol. 50, Issue 8, pp. 1555-65, (2014) (PubMed).

Rountree, Bachman, Baylin: "DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci." in: Nature genetics, Vol. 25, Issue 3, pp. 269-77, (2000) (PubMed).

Synonyms and alternative names related to DMAP1

DNA methyltransferase 1-associated protein DMAP1 (AFUA_4G07380), DNA methyltransferase 1-associated protein DMAP1 (NFIA_108840), DNA methyltransferase 1-associated protein DMAP1 (ACLA_046700), DNA methyltransferase 1-associated protein 1 (CpipJ_CPIJ017959), DNA methyltransferase 1 associated protein 1 (Bm1_47540), DNA methyltransferase 1-associated protein DMAP1 (PMAA_026820), DNA methyltransferase 1-associated protein DMAP1 (AFLA_112450), DNA methyltransferase 1-associated protein DMAP1 (TSTA_072020), DNA methyltransferase 1-associated protein DMAP1 (BDBG_02603), myb-like transcription factor family protein (AT2G47210), DNA methyltransferase 1-associated protein 1 (CpipJ_CPIJ007438), DNA methyltransferase 1 associated protein 1 (DMAP1), DNA methyltransferase 1 associated protein 1 (dmap1), DNA methyltransferase 1 associated protein 1 L homeolog (dmap1.L), DNA methyltransferase 1-associated protein 1 (Dmap1), 1500016M21Rik, Afu4g07380, Dmtap1, DNMAP1, dnmap1, DNMTAP1, dnmtap1, EAF2, eaf2, MEAF2, meaf2, mKIAA1425, SWC4, swc4, T8I13.5, zgc:55593

Protein level used designations for DMAP1

  • DNA methyltransferase 1-associated protein DMAP1
  • DNA methyltransferase 1-associated protein 1
  • DNA methyltransferase 1 associated protein 1
  • DNMT1 associated protein 1
  • DNMT1-associated protein 1
  • DNMT1 associated protein-1
  • MAT1-mediated transcriptional repressor
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