(Discs, Large (Drosophila) Homolog-Associated Protein 4 (DLGAP4))
The product of this gene is a membrane-associated guanylate kinase found at the postsynaptic density in neuronal cells. It is a signaling molecule that can interact with potassium channels and receptors, as well as other signaling molecules. The protein encoded by this gene can interact with PSD-95 through its guanylate kinase domain and may be involved in clustering PSD-95 in the postsynaptic density region. The encoded protein is one of at least four similar proteins that have been found. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Bongiorno-Borbone, Kadaré, Benfenati, Girault: "FAK and PYK2 interact with SAP90/PSD-95-Associated Protein-3." in: Biochemical and biophysical research communications, Vol. 337, Issue 2, pp. 641-6, (2005) (PubMed).
Kindler, Rehbein, Classen, Richter, Böckers: "Distinct spatiotemporal expression of SAPAP transcripts in the developing rat brain: a novel dendritically localized mRNA." in: Brain research. Molecular brain research, Vol. 126, Issue 1, pp. 14-21, (2004) (PubMed).
Ranta, Zhang, Ross, Takkunen, Hirvasniemi, de la Chapelle, Gilliam, Lehesjoki: "Positional cloning and characterisation of the human DLGAP2 gene and its exclusion in progressive epilepsy with mental retardation." in: European journal of human genetics : EJHG, Vol. 8, Issue 5, pp. 381-4, (2000) (PubMed).
Aliases for DLGAP4 抗体
DLG associated protein 4 (DLGAP4) 抗体 discs, large (Drosophila) homolog-associated protein 4 (DLGAP4) 抗体 DLG associated protein 4 (dlgap4) 抗体 discs, large homolog-associated protein 4 (Drosophila) (Dlgap4) 抗体 DLG associated protein 4 (Dlgap4) 抗体 AI225853 抗体 BC024558 抗体 DAP-4 抗体 DAP4 抗体 Dap4 抗体 DKFZp469I1627 抗体 DLP4 抗体 MGC155295 抗体 RP5-977B1.6 抗体 SAPAP-4 抗体 SAPAP4 抗体 Sapap4 抗体 WBP16 抗体