The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and multiple transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2010].
Li, Urs, Allegood, Leon, Merrill, Sewer: "Cyclic AMP-stimulated interaction between steroidogenic factor 1 and diacylglycerol kinase theta facilitates induction of CYP17." in: Molecular and cellular biology, Vol. 27, Issue 19, pp. 6669-85, (2007) (PubMed).
Hogan, Shepherd, Chabot, Quenneville, Prescott, Topham, Gee: "Interaction of gamma 1-syntrophin with diacylglycerol kinase-zeta. Regulation of nuclear localization by PDZ interactions." in: The Journal of biological chemistry, Vol. 276, Issue 28, pp. 26526-33, (2001) (PubMed).