The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidic acid. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008].
Karere, Glenn, Birnbaum, Hafizi, Rainwater, Mahaney, VandeBerg, Cox: "Identification of candidate genes encoding an LDL-C QTL in baboons." in: Journal of lipid research, Vol. 54, Issue 7, pp. 1776-85, (2013) (PubMed).
Alonso, Mazzeo, Rodriguez, Marsh, Fraile-Ramos, Calvo, Avila-Flores, Merida, Izquierdo: "Diacylglycerol kinase ? regulates the formation and polarisation of mature multivesicular bodies involved in the secretion of Fas ligand-containing exosomes in T lymphocytes." in: Cell death and differentiation, Vol. 18, Issue 7, pp. 1161-73, (2011) (PubMed).
Guckes, McCarthy, Brahim: "Use of endosseous implants in a 3-year-old child with ectodermal dysplasia: case report and 5-year follow-up." in: Pediatric dentistry, Vol. 19, Issue 4, pp. 282-5, (1997) (PubMed).
McGlade: "A guide to parents' participation in pediatric imaging." in: Radiology management, Vol. 19, Issue 1, pp. 46-9, (1997) (PubMed).