DEFA6 抗体
(Defensin, alpha 6, Paneth Cell-Specific (DEFA6))
Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 6, is highly expressed in the secretory granules of Paneth cells of the small intestine, and likely plays a role in host defense of human bowel. [provided by RefSeq, Jul 2008].
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Latest Publications for our DEFA6 抗体
: "Human Defensin-5 Blocks Ethanol and Colitis-Induced Dysbiosis, Tight Junction Disruption and Inflammation in Mouse Intestine." in: Scientific reports, Vol. 8, Issue 1, pp. 16241, (2018) (PubMed).: "REG gene expression in inflamed and healthy colon mucosa explored by in situ hybridisation." in: Cell and tissue research, Vol. 352, Issue 3, pp. 639-46, (2013) (PubMed).
: "Macaque paneth cells express lymphoid chemokine CXCL13 and other antimicrobial peptides not previously described as expressed in intestinal crypts." in: Clinical and vaccine immunology : CVI, Vol. 20, Issue 8, pp. 1320-8, (2013) (PubMed).
: "Activation of REG family proteins in colitis." in: Scandinavian journal of gastroenterology, Vol. 46, Issue 11, pp. 1316-23, (2011) (PubMed).
Aliases for DEFA6 抗体
defensin alpha 6 (DEFA6) 抗体defensin, alpha 6, Paneth cell-specific (DEFA6) 抗体
defensin alpha 6 (Defa6) 抗体
defensin, alpha, 6 (Defa6) 抗体
DEF6 抗体
DEFA6 抗体
Defcr6 抗体
HD-6 抗体
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