DEFA5 抗体
(Defensin, alpha 5, Paneth Cell-Specific (DEFA5))
Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum. [provided by RefSeq, Jul 2008].
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41 results
DEFA5
适用: 人
ELISA, ICC, IHC (p), IHC (fro), IF (cc), IF (p)
宿主: 兔
Polyclonal
unconjugated
Latest Publications for our DEFA5 抗体
: "Alarin in different human intestinal epithelial cell types." in: Histochemistry and cell biology, (2019) (PubMed).: "Alpha-defensins (α-Defs) in Crohn's disease: decrease of ileal α-Def 5 via permanent methylation and increase in plasma α-Def 1-3 concentrations offering biomarker utility." in: Clinical and experimental immunology, (2018) (PubMed).
: "LRRK2 but not ATG16L1 is associated with Paneth cell defect in Japanese Crohn's disease patients." in: JCI insight, Vol. 2, Issue 6, pp. e91917, (2017) (PubMed).
: "Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling." in: Cell stem cell, Vol. 21, Issue 1, pp. 51-64.e6, (2017) (PubMed).
: "Paneth cell defects in Crohn's disease patients promote dysbiosis." in: JCI insight, Vol. 1, Issue 8, pp. e86907, (2016) (PubMed).
: "Lowered expression of galectin-2 is associated with lymph node metastasis in gastric cancer." in: Journal of gastroenterology, Vol. 47, Issue 1, pp. 37-48, (2012) (PubMed).
: "Profiling of differentially expressed proteins in stage IV colorectal cancers with good and poor outcomes." in: Journal of proteomics, Vol. 75, Issue 10, pp. 2983-97, (2012) (PubMed).
: "[Identification of protein markers for serum diagnosis of cancer based on microRNA expression profiling]." in: Molekuliarnaia biologiia, Vol. 45, Issue 2, pp. 376-81, (2011) (PubMed).
: "Gene expression profiling of metaplastic lineages identifies CDH17 as a prognostic marker in early stage gastric cancer." in: Gastroenterology, Vol. 139, Issue 1, pp. 213-25.e3, (2010) (PubMed).
: "Paneth cell antimicrobial peptides: topographical distribution and quantification in human gastrointestinal tissues." in: FEBS letters, Vol. 580, Issue 22, pp. 5344-50, (2006) (PubMed).
Aliases for DEFA5 抗体
defensin alpha 5 (DEFA5) 抗体defensin, alpha, 5 (Defa5) 抗体
defensin, alpha 5, Paneth cell-specific (DEFA5) 抗体
defensin alpha 5 (Defa5) 抗体
alpha-defensin 1A (MNP1A) 抗体
DEF5 抗体
Defa 抗体
DEFA1 抗体
DEFA5 抗体
Defa29 抗体
Defcr5 抗体
Defcr29 抗体
HD-5 抗体
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